group photo 

Members of the Mark Tuszynski Lab.

Most Important Research Papers

  • Tuszynski MH et al.  A phase I clinical trial of nerve growth factor gene therapy for Alzheimer’s disease. Nature Medicine, 2005, 11:551-5.

  • Nagahara A, Merrill DA, Coppola G, Tsukada S, Schroder BE, Shaked GM, Wang L, Blesch A, Kim A, Conner JC, Rockenstein E, Chao MV, Koo E, Geschwind D, Masliah, Chiba AA, Tuszynski MH. Neuroprotective effects of BDNF in rodent and primate models of Alzheimer’s disease. Nature Medicine, 2009, 15:331-337. PMCID: PMC2838375. 

  • Alto L, Havton LA, Conner JM, Hollis ER, Blesch A, Tuszynski MH. Chemotropic guidance facilitates axonal regeneration into brainstem targets and synapse formation after spinal cord injury. Nature Neuroscience, 2009, 12: 1106-1113. PMCID 2753201.

  • Rosenzweig ES, Courtine G, Jindrich DL, Brock JH, Ferguson AR, Strand SC, Nout YS, Roy RR, Miller DM, Beattie MS, Havton LA, Bresnahan JC, Edgerton VR, Tuszynski M. Extensive spontaneous plasticity of corticospinal projections after primate spinal cord injury. Nature Neuroscience, 2010, 13:1505-1510.

  • Wang L, Conner JM, Rickert JL, Tuszynski MH. Structural plasticity within highly specific neuronal populations identifies a parcellation of motor learning. Proc Nat Acad Sci, 2011, 108:2545-2550. PMCID: PMC3038698.

  • Lu P, Wang Y, Graham L, McHale K, Gao M, Wu D, Brock J, Blesch A, Rosenzweig ES, Havton LA, Zheng B, Conner JM, Marsala M, Tuszynski MH. Long-distance growth and connectivity of neural stem cells after severe spinal cord injury: Cell-intrinsic mechanisms overcome spinal inhibition. Cell  2012, 14;150:1264-73. PMCID: PMC3445432.

  • Lu P, Woodruff G, Wang Y, Graham L, Hunt M, Wu D, Boehle E, Ahmad R, Poplawski G, Brock J, Goldstein LSB, Tuszynski MH. Long-distance axonal growth from human induced pluripotent stem cells after spinal cord injury. Neuron, 2014; 83:789-96.

  • Tuszynski MH, Yang JH, Barba D, U HS, Bakay R, Pay MM, Masliah E, Conner JM, Kobalka P, Roy S, Nagahara AH. Neuronal responses to nerve growth factor gene therapy in Alzheimer’s disease.  JAMA Neurology  2015; in press. Biane JS, Takashima Y, Conner JM, Massimo Scanziani,

  • Tuszynski MH. Thalamocortical projections exhibit plasticity onto behaviorally-relevant neurons during adult motor learning. Neuron 2016, in press.

  • Kadoya K, Paul Lu P,  Nguyen K, Lee-Kubli C, Yao L, Poplawski G, Dulin J, Takashima Y, Biane J, Conner J, Zhang S-C, Tuszynski MH. Robust corticospinal regeneration enabled by spinal cord reconstitution with homologous neural grafts. Nature Medicine, 2016, in press.


Contact Us 
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Mark Tuszynski MD, PhD, Director
Professor of Neurosciences
UC San Diego
La Jolla, California 92093-0626

Takae Sekido,
Executive Assistant
(858) 534-8857
Fax: (858) 534-5220