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Research Outcomes

During the last years, the exponential grow of Neuroepigenetics demonstrated the involvement of DNA methylation and histone modifications on the pathology of a variety of neurological diseases — and importantly, proved their relevance in post-mitotic cells in the human brain. The work of our lab reporting mislocalization of DNA methyltransferase 1 in the brains of Parkinson’s disease (PD) patients was among a few pioneer studies focused on epigenetic mechanisms disrupted in neurodegeneration (Desplats et al 2008 JBC).

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Our Team

Desplats and her lab team

Meet the Team