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Desplats Lab Research

Our Work

Research in our lab is aimed at elucidating the dynamic mechanisms of DNA methylation, which might contribute to onset and progression of the most prevalent neurodegenerative diseases of the elderly, Parkinson’s and Alzheimer’s.

At the center of our work is a strong interest in translational neuroscience, therefore we combine aspects of cellular physiology and molecular neuroscience, integrating the analysis of human postmortem brain samples, transgenic animals and cellular models to address mechanistic questions, while identifying therapeutic targets and providing novel diagnostic tools.

Research Opportunities

Come join us at the forefront of discovery and share the excitement of learning neuroepigenetics and understanding neuronal molecular mechanisms!

Masters student candidates

The Desplats Lab is looking for candidates for the UC San Diego Master in Sciences program and to perform research projects for BISP 196 Honors Thesis.

  • Previous experience in a research laboratory is required, with proficiency in biochemistry and molecular biology techniques.
  • Experience with tissue culture is a plus.
  • Must have GPA above 3.0 and completed general biology courses.

Undergraduate candidates

We are also seeking undergraduate students interested in completing short research projects for academic credits, through NEU 199, BISP 199 or similar programs.

  • Minimal experience at the bench required
  • Good GPA scores and at least 15 h/week to dedicate to the lab
  • Priority will be given to students willing to commit for 2 quarters as part of the Faculty Mentor Program (FMP)