ABCD-Assessing Novel Biomarkers for Cognitive Fluctuations in DLB & AD

 Study Summary
We are doing a research study that follows people over time at several different locations. The goal is to better understand changes in thinking and alertness in people living with dementia with Lewy bodies (DLB) or Alzheimer’s disease (AD).

What is the main purpose of the study?
We want to compare two ways of measuring day-to-day changes in thinking and awareness:

1. Reports from family members or caregivers, and

2. Information collected from new wearable or real-time devices.

By following participants over time, we hope to learn whether these new devices can reliably detect cognitive fluctuations and how they compare to caregiver observations. This may help improve diagnosis and monitoring of DLB and AD in the future.

Actigraphy/wearable devices:

• How it Works: Uses an accelerometer to detect body movement, inferring sleep (lack of movement) and wakefulness (movement).
• Purpose: Assesses sleep quality, duration, and timing; detects insomnia, jet lag, shift work issues, and circadian rhythm disorders.

Features: Often includes light sensors (for ambient light), temperature sensors, and event markers, with data uploaded to a computer