Enrolling Studies
- Clinical Trials
- Observational Studies
- Research Procedures
- Research Registry
- Frequently Asked Questions
Currently Enrolling Observational Studies
Research Opportunites by Diagnosis
The Shiley-Marcos Alzheimer’s Disease Research Center has a wide variety of opportunities for volunteers to participate in important research studies designed to discover ways to prevent, treat, and ultimately eradicate Alzheimer’s disease as well as other related neurological diseases. We are recruiting diverse volunteers on an ongoing basis to learn more about memory and aging.
Healthy adults with NO memory concerns - Normal Cognition (NC)
- Cognitive Aging Longitudinal Study (in English and Spanish)
- Alzheimer's Disease Neuroimaging Initiative (ADNI 4)
- The Blood-brain Barrier in Alzheimer's Disease
- Cerebral Blood Flow & Arterial compliance in Alzheimer's Disease Risk
- Olfactory and Visual Dysfunction as Potential Predictors of Preclinical AD
- Vascular and Biomarker Influences on Cognitive Aging
- Novel Cognitive Markers of Early Alzheimer's Disease
- Subjective Cognitive Decline (Latinx participants in English and Spanish)
- Diverse Vascular Cognitive Impairment and Dementia (DVCID) (English and Spanish)
- HALT-AD
- Aging, Memory, and Social Connection
- The Effects of COVID 19 on Brain Imaging
- DIAD - Digital Detection of Social Isolation and Loneliness Markers of Risk for Alzheimer's Disease
- Induced Pluripotent Stem Cells
- American Gut Microbiome - The Brain-Gut Connection
Mild Cognitive Impairment (MCI)
- Cognitive Aging Longitudinal Study (in English and Spanish)
- Alzheimer's Disease Neuroimaging Initiative (ADNI 4)
- The Blood-brain Barrier in Alzheimer's Disease
- Women: Inflammation and Tau Study (WITS)
- Cerebral Blood Flow & Arterial compliance in Alzheimer's Disease Risk
- Olfactory and visual dysfunction as potential predictors of preclinical AD
- Vascular and Biomarker Influences on Cognitive Aging
- Gamma Neurofeedback Intervention to Improve Memory in Mild Cognitive Impairment
- Novel Cognitive Markers of Early Alzheimer's Disease
- Subjective Cognitive Decline (Latinx participants in English and Spanish)
- Diverse Vascular Cognitive Impairment and Dementia (DVCID) (in English and Spanish)
- Aging, Memory, and Social Connection
- SYN-D
- TREAD-Time Restricted Eating in Alzheimer's Disease
- Induced Pluripotent Stem Cells
- American Gut Microbiome - The Brain-Gut Connection
Alzheimer's disease (AD)
- Cognitive Aging Longitudinal Study (in English and Spanish)
- Alzheimer's Disease Neuroimaging Initiative (ADNI 4)
- The Blood-brain Barrier in Alzheimer's Disease
- Women: Inflammation and Tau Study (WITS)
- TREAD-Time Restricted Eating in Alzheimer's Disease
- Induced Pluripotent Stem Cells
- American Gut Microbiome - The Brain-Gut Connection
Young onset Alzheimer's disease (younger than 65 years at onset)
Parkinson's disease
Lewy Body Dementia (LBD)
Frontotemporal & other dementias
Memory concerns NO diagnosis
Many seniors have concerns about their memories and wonder if the changes they are experiencing are normal age-related changes or whether they may be the early signs of a disease process. If you are concerned about your memory and would like to have an assessment please inquire about our free memory screening events.
If you are interested in research participation, the SMADRC includes persons with and without memory loss in our observational longitudinal study listed below. This study will provide detailed feedback about the cognitive status on an annual basis
Downs Syndrome
Research Registry
If you are interested in any of our current studies or you'd like to participate in a study but don't currently see one that is a match for you, join our research registry to be placed on a list for future studies.
For more information contact:
Phone: 858-822-4800Email: participate@ucsd.edu