iPSC-Induced Pluripotent Stem Cells to Study Human Models of Aging and Disease
| Study Name | iPSC-Induced Pluripotent Stem Cells to Study Human Models of Aging and Disease |
| Study Summary | You are being asked to provide skin cells from your forearm or the back of your tricep for the purpose of generating human pluripotent stem cells. These stem cells will be used to generate human brain cells (neurons) in the laboratory that have the same genetic makeup as you do. None of the skin cells you provide will be used to produce a human pregnancy or a cloned human person. We hope to create a ‘laboratory model’ using all of the genes from donors; they may help us study the causes of various diseases and test new medications and therapies. As part of this study, we will also be determining your genetic makeup by analyzing your DNA (DNA is the genetic material inside of your cells). |
| Principal Investigator(s) | Douglas Galasko, MD |
| Required Diagnosis | SMADRC longitudinal study ENROLLED participants with a diagnosis of Normal Cognition, Mild Cognitive Impairment (MCI), Alzheimer's disease (AD). or Down Syndrome (DS) |
| Age | 65 or older for Normal Controls; N/A for persons with diagnosis |
| Length | one time appointment |
| Lumbar Puncture | No |
| MRI | No |
| Amyloid PET | No |
| Tau PET | No |
| Compensation | No |
| Contact | |
| More Information |
Video about the Skin Biopsy Procedure Video about iPSC Research |
| Aftercare Instructions |