TREAD-Time Restricted Eating in Alzheimer's Disease
| Study Name | TREAD-Time Restricted Eating in Alzheimer's Disease | |
| Study Summary |
The purpose of this study is to investigate the safety, feasibility, and effectiveness of prolonged night fasting in reducing cognitive decline and disease markers in patients with mild cognitive impairment (MCI) or early to moderate Alzheimer’s disease (AD). Participants will be randomized into two groups and will follow a time-restricted eating (TRE) model of prolonged fasting during the night for 6 or 12 months. We will monitor blood-based markers of health, metabolism, aging, and AD pathology; record circadian regulation based on sleep and activity monitoring, and evaluate cognitive functions. |
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| Principal Investigator(s) | Paula Desplats Ph.D. | |
| Required Diagnosis | Mild Cognitive Impairment (MCI), early stage Alzheimer's disease (AD) OR are healthy and are the living partner/spouse of a person diagnosed with Mild Cognitive Impairment or Alzheimer's Disease | |
| Age | 65 or older | |
| Length | 1 year | |
| Lumbar Puncture | No | |
| MRI | No | |
| Amyloid PET | No | |
| Tau PET | No | |
| Compensation | Yes | |
| Contact | ||
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