Research Publications
Wide-ranging research techniques and topics published in leading journals
Our center publishes research findings that capitalize on a wide range of research techniques and span many topics in autism — for example, our research studies examine behavior using eye tracking technology, brain imaging using magnetic resonance imaging (MRI) and genetics.
2023
Level of attention to motherese speech as an early marker of autism spectrum disorder
Pierce, K., Wen, T.H., Zahiri, J; et al. Level of attention to motherese speech as an early marker of autism spectrum disorder.
2022
Large scale validation of an early-age eye-tracking biomarker of an autism spectrum disorder subtype
Wen TH, Cheng A, Andreason C, Zahiri J, Xiao Y, Xu R, Bao B, Courchesne E, Barnes CC, Arias SJ, Pierce K. Large scale validation of an early-age eye-tracking biomarker of an autism spectrum disorder subtype. Sci Rep. 2022 Mar 11;12(1):4253. doi: 10.1038/s41598-022-08102-6.
Neural responses to affective speech, including motherese, map onto clinical and social eye tracking profiles in toddlers with ASD
Xiao, Y., Wen, T.H., Kupis, L., Eyler, L.H., Goel, D., Vaux, K., Lombardo, M.V., Lewis, N.E., Pierce, K., and Courchesne, E. Neural responses to affective speech, including motherese, map onto clinical and social eye tracking profiles in toddlers with ASD. Nat Hum Behav (2022). https://doi.org/10.1038/s41562-021-01237-y
2021
Prevalence and Characteristics of Autism Spectrum Disorder Among Children Aged 8 Years — Autism and Developmental Disabilities Monitoring Network
Maenner MJ, Shaw KA, Bakian AV, et al. Prevalence and Characteristics of Autism Spectrum Disorder Among Children Aged 8 Years — Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2018. MMWR Surveill Summ 2021;70(No. SS-11):1–16. DOI: http://dx.doi.org/10.15585/mmwr.ss7011a1.
Early Identification of Autism Spectrum Disorder Among Children Aged 4 Years — Autism and Developmental Disabilities Monitoring Network
Shaw KA, Maenner MJ, Bakian AV, et al. Early Identification of Autism Spectrum Disorder Among Children Aged 4 Years — Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2018. MMWR Surveill Summ 2021;70(No. SS-10):1–14. DOI: http://dx.doi.org/10.15585/mmwr.ss7010a1.
Large-scale Targeted Sequencing Identifies Risk Genes for Neurodevelopmental Disorders
Lombardo M. V., Eyler L., Pramparo T., Gazestani V. H., Hagler D. J., Jr., Chen C. H., Dale, A., Seidlitz, J., Bethlehem, R.A., Bertelsen, N., Carter Barnes, C., Lopez, L., Campbell, K., Lewis, N., Pierce, K. & Courchesne, E. Atypical genomic cortical patterning in autism with poor early language outcome. Science Advances. 2021;7:eabh1663 PMC8442861.
Pre-treatment clinical and gene expression patterns predict developmental change in early intervention in autism
Lombardo, M., Busuoli, E., Schreibman, L., Stahmer, A., Pramparo, T., Landi, I., Mandelli, V., Bertelsen, N., Carter Barnes, C., Gazestani, V., Lopez, L., Bacon, E., Courchesne, E., and Pierce, K. (2021). Pre-treatment clinical and gene expression patterns predict developmental change in early intervention in autism. Molecular Psychiatry. 2021 Aug 2. doi: 10.1038/s41380-021-01239-2. Online ahead of print. PMID: 34341515.
Get SET Early to identify and treatment refer autism spectrum disorder at 1 year and discover factors that influence early diagnosis
Pierce, K., Gazestani, V., Bacon, E., et al., (2021). Get SET Early to identify and treatment refer autism spectrum disorder at 1 year and discover factors that influence early diagnosis. Journal of Pediatrics, doi:10.1016/j.jpeds.2021.04.041. On-line ahead of print.
2020
Large-scale Targeted Sequencing Identifies Risk Genes for Neurodevelopmental Disorders
Tianyun Wang, Karen Pierce, Eric Courchesne. Large-scale targeted sequencing identifies risk genes for neurodevelopmental disorders Nat Commun. 2020; 11: 4932. Published online 2020 Oct 1. doi: 10.1038/s41467-020-18723-y.
Prenatal Origins of ASD: The When, What, and How of ASD Development
Eric Courchesne, Vahid H Gazestani, Nathan E Lewis Prenatal Origins of ASD: The When, What, and How of ASD Development. Trends Neurosci. 2020 May;43(5):326-342. doi: 10.1016/j.tins.2020.03.005.
Identifying Prognostic Markers in Autism Spectrum Disorder Using Eye Tracking
Bacon E.C., Moore A., Lee Q., Carter Barnes C., Courchesne E., Pierce K. Identifying prognostic markers in autism spectrum disorder using eye tracking. Autism. 2020 Apr;24(3):658-669. doi: 10.1177/1362361319878578.
Psychiatric and Medical Profiles of Autistic Adults in the SPARK Cohort
Fombonne E, Green Snyder L, Daniels A, Feliciano P, Chung W; SPARK Consortium. Psychiatric and Medical Profiles of Autistic Adults in the SPARK Cohort [published online ahead of print, 2020 Feb 24]. J Autism Dev Disord. 2020;10.1007/s10803-020-04414-6. doi:10.1007/s10803-020-04414-6.
Beliefs in Vaccine as Causes of Autism Among SPARK Cohort Caregive
Fombonne E, Goin-Kochel RP, O'Roak BJ; SPARK Consortium. Beliefs in vaccine as causes of autism among SPARK cohort caregivers. Vaccine. 2020 Feb 11;38(7):1794–1803. doi:10.1016/j.vaccine.2019.12.026.
2019
Default Mode-visual network hypoconnectivity in an autism subtype with pronounced social visual engagement difficulties
Lombardo M.V., Eyler L., Moore A., Datko M., Carter Barnes C., Cha D., Courchesne E., Pierce K. Default mode-visual network hypoconnectivity in an autism subtype with pronounced social visual engagement difficulties. Elife. 2019 Dec 17;8. doi: 10.7554/eLife.47427.
Clinical Practice Guideline for the Diagnosis, Evaluation, and Treatment of Attention-Deficit/Hyperactivity Disorder in Children and Adolescents
Wolraich ML, Hagan JF, Allan C, et al; Subcommittee on Children and Adolescents with Attention-Deficit/Hyperactive Disorder. Clinical Practice Guideline for the Diagnosis, Evaluation, and Treatment of Attention-Deficit/Hyperactivity Disorder in Children and Adolescents. Pediatrics. 2019;144(4). doi: 10.1542/peds.2019-2528.
A Perturbed Gene Network Containing PI3K-AKT, RAS-ERK and WNT-B-catenin Pathways in Leukocytes is Linked to ASD Genetics and Symptom Severity
Gazestani, V.H., Pramparo, T., Nalabolu, S., Kellman, B.P., Murray, S., Lopez, L., Pierce, K., Courchesne, E., Lewis, N.E. A Perturbed Gene Network Containing PI3K-AKT, RAS-ERK and WNT-B-catenin Pathways in Leukocytes is Linked to ASD Genetics and Symptom Severity. Nature Neuroscience 22, 1624-1634 (2019). doi:10.1038/s41593-019-0489-x.
Evaluation of the Diagnostic Stability of the Early Autism Spectrum Disorder Phenotype in the General Population Starting at 12 Months
Pierce, K., Gazestani, V.H., Bacon, E., Barnes, C.C., Cha, D., Nalabolu, S., Lopez, L., Moore, A., Pence-Stophaeros, S., Courchesne, E. Evaluation of the Diagnostic Stability of the Early Autism Spectrum Disorder Phenotype in the General Population Starting at 12 Months. JAMA Pediatr. Published online April 29, 2019. doi:10.1001/jamapediatrics.2019.0624.
Big Data Approaches to Decomposing Heterogeneity Across the Autism Spectrum
Lombardo, M. V., Lai, M., & Baron-Cohen, S. (2019). Big data approaches to decomposing heterogeneity across the autism spectrum. Molecular Psychiatry. doi:10.1038/s41380-018-0321-0.
2018
The ASD Living Biology: From cell proliferation to clinical phenotype
Courchesne, E., Pramparo, T., Gazestani, V. H., Lombardo, M. V., Pierce, K., & Lewis, N. E. (2018).The ASD Living Biology: From cell proliferation to clinical phenotype. Molecular Psychiatry, 24(1), 88-107. doi:10.1038/s41380-018-0056-y.
The Geometric Preference Subtype in ASD: Identifying a Consistent, Early-Emerging Phenomenon Through Eye Tracking
Moore, A., Wozniak, M., Yousef, A., Barnes, C. C., Cha, D., Courchesne, E., & Pierce, K. (2018). The geometric preference subtype in ASD: identifying a consistent, early-emerging phenomenon through eye tracking. Molecular Autism, 9, 19. PMID: 29581878.
2017
Rethinking the Idea o Late Autism Spectrum Disorder Onset
Bacon, E. C., Courchesne, E., Barnes, C. C., Cha, D., Pence, S., Schreibman, L., Stahmer, A. & Pierce, K. (2017). Rethinking the idea of late autism spectrum disorder onset. Development and psychopathology, 1-17. PMID: 28803559.
Toddlers Later Diagnosed with Autism Exhibit Structural Abnormalities in Temporal, Frontal, and Occipital Corpus Callosum Fibers
Fingher, N., Dinstein, I., Ben-Shachar, M., Haar, S., Dale, A. M., Eyler, L., Pierce, K., Dale, A. & Courchesne, E. (2017). Toddlers later diagnosed with autism exhibit multiple structural abnormalities in temporal corpus callosum fibers. Cortex, 97, 291-305. PMID: 28202133.
Heirarchical Cortical Transcriptome Disorganization in Autism
Lombardo, M. V., Courchesne, E., Lewis, N. E., & Pramparo, T. (2017). Hierarchical cortical transcriptome disorganization in autism. Molecular autism, 8(1), 29. PMID: 28649314.
Maternal Immune Activation Dysregulation of the Fetal Brain Transcriptome and Relevance to the Pathophysiology of Autism Spectrum Disorder
Lombardo, M. V., Moon, H. M., Su, J., Palmer, T. D., Courchesne, E., & Pramparo, T. (2017). Maternal immune activation dysregulation of the fetal brain transcriptome and relevance to the pathophysiology of autism spectrum disorder. Molecular psychiatry. PMID: 28322282.
2016
To Screen or Not to Screen for ASD Universally is Not the Question: Why the Task Force Got it Wrong
Pierce K, Courchesne E, Bacon E.To Screen or Not to Screen for ASD Universally is Not the Question: Why the Task Force Got it Wrong. The Journal of pediatrics. 2016;176:182-194. doi:10.1016/j.jpeds.2016.06.004.
Diffusion Tensor Imaging Provides Evidence of Possible Axonal Overconnectivity in Frontal Lobes in Autism Spectrum Disorder Toddlers
Solso, S., Xu, R., Proudfoot, J., Hagler, D. J., Campbell, K., Venkatraman, V., ... & Eyler, L. (2016). Diffusion tensor imaging provides evidence of possible axonal overconnectivity in frontal lobes in autism spectrum disorder toddlers. Biological psychiatry, 79(8), 676-684. PMID: 26300272.
2015
Eye Tracking Reveals Abnormal Visual Preference for Geometric Images as an Early Biomarker of an Autism Spectrum Disorder Subtype Associated with Increased Symptom Severity
Pierce K, Marinero S, Hazin R, McKenna B, Barnes C, Malige A. Eye Tracking Reveals Abnormal Visual Preference for Geometric Images as an Early Biomarker of an Autism Spectrum Disorder Subtype Associated with Increased Symptom Severity. Biological Psychiatry. 2015 Apr 11. doi: 10.1016/j.biopsych.2015.03.032.
Prediction of Autism by translation and Immune/Inflammation Coexpressed Genes in Toddlers From Pediatric Community
Pramparo T, Pierce K, Lombardo MV, et al. Prediction of Autism by Translation and Immune/Inflammation Coexpressed Genes in Toddlers From Pediatric Community Practices. JAMA Psychiatry. Published online March 04, 2015. doi:10.1001/jamapsychiatry.2014.300.
Different Functional Neural Substrates for Good and Poor Language Outcome in Autism
Lombardo, M., Pierce, K., Eyler, L., Barnes, C, Ahrens-Barbeau, C., Solso, S., Campbell, K., & Courchesne, E. (2015). Different functional neural substrates for good and poor language outcome in autism. Neuron, 86(2), 567-577.
2014
Measuring Outcomes in an Early Intervention Program for Young Children with Autism Spectrum Disorder: Use of a Curriculum-Based Assessment
Bacon, L., Dufek, S., Schreibman, L. Stahmer, A., Pierce, K. and Courchesne, E. (2014). Measuring Outcomes in an Early Intervention Program for Young Children with Autism Spectrum Disorder: Use of a Curriculum-Based Assessment. Autism Research and Treatment. PMID: 24711926, PMCID: PMC3966353.
Patches of Disorganization in the Neocortex of Children with Autism
Rich Stoner, Maggie L. Chow, Maureen P. Boyle, Susan M. Sunkin, Peter R. Mouton, Subhojit Roy, Anthony Wynshaw-Boris, Sophia A. Colamarino, Ed S. Lein, and Eric Courchesne. Patches of Disorganization in the Neocortex of Children with Autism.N Engl J Med. 2014 Mar 27; 370:1209-19. DOI: 10.1056/NEJMoa1307491.
2012
Blood-based Gene Expression Signatures of Infants and Toddlers with Autism
Glatt SJ, Tsuang MT, Winn M, Chandler SD, Collins M, Lopez L, Weinfeld M, Carter C, Schork N, Pierce K, Courchesne E. Blood-based gene expression signatures of infants and toddlers with autism. J Am Acad Child Adolesc Psychiatry. 2012 Sep;51(9):934-44.e2. doi: 10.1016/j.jaac.2012.07.007. Epub 2012 Aug 2.
Abnormal microglial-neuronal spatial organization in the dorsolateral prefrontal cortex in autism
Morgan, JT, Chana G, Abramson I, Semendeferi K, Courchesne E, Everall IP. Abnormal microglial-neuronal spatial organization in the dorsolateral prefrontal cortex in autism. Brain Res. 2012 May 25:1456:72-81. doi: 10.1016/j.brainres.2012.03.036. Epub 2012 Mar 23.
Age-dependent brain gene expression and copy number anomalies in autism suggest distinct pathological processes at young versus mature ages
Chow ML, Pramparo T, Winn ME, Barnes CC, Li HR, Weiss L, Fan JB, Murray S, April C, Belinson H, Fu XD, Wynshaw-Boris A, Schork NJ, Courchesne E. Age-dependent brain gene expression and copy number anomalies in autism suggest distinct pathological processes at young versus mature ages. PLoS Gen. 2012;8(3).doi: 10.1371/journal.pgen.1002592. Epub 2012 Mar 22.
Preprocessing and Quality Control Strategies for Illumina DASL Assay-Based Brain Gene Expression Studies with Semi-Degraded Samples
Chow ML, Winn ME, Li HR, April C, Wynshaw-Boris A, Fan JB, Fu XD, Courchesne E, Schork NJ. Preprocessing and Quality Control Strategies for Illumina DASL Assay-Based Brain Gene Expression Studies with Semi-Degraded Samples. Front Genet. 2012;3:11. doi: 10.3389/fgene.2012.00011.
A failure of left temporal cortex to specialize for language is an early emerging and fundamental property of autism
Eyler LT, Pierce K, Courchesne E. A failure of left temporal cortex to specialize for language is an early emerging and fundamental property of autism. Brain. 2012 Mar;135(Pt 3):949-60. doi: 10.1093/brain/awr364. Epub 2012 Feb 20.
2011
Courchesne E, Mouton PR, Calhoun ME, Semendeferi K, Ahrens-Barbeau C, Hallet MJ, Barnes CC, Pierce K. Neuron number and size in prefrontal cortex of children with autism. JAMA. 2011 Nov 9;306(18):2001-10. PubMed PMID: 22068992.
Chow ML, Li HR, Winn ME, April C, Barnes CC, Wynshaw-Boris A, Fan JB, Fu XD, Courchesne E, Schork NJ. Genome-wide expression assay comparison across frozen and fixed postmortem brain tissue samples. BMC Genomics. 2011 Sep 10;12:449. PubMed PMID: 21906392; PubMed Central PMCID: PMC3179967.
Pierce, K., Carter, C., Weinfeld, M., Desmond, J., Hazin, R., Bjork, R., Gallagher, N. Detecting, studying, and treating autism early: the one-year well-baby check-up approach. Journal of Pediatrics, 158:5, 2011.
Pierce, K., Conant, D., Hazin, R., Desmond, J., & Stoner, R. A preference for geometric patterns early in life as a risk factor for autism. Archives of General Psychiatry. 68(1):101-9, 2011.
Courchesne, E., Campbell, K., Solso, S. Brain growth across the life span in autism: Age-specific changes in anatomical pathology. Brain Research, 1380:138-45, 2011.
Delahanty, R.J., Kang, J.Q., Brune, C.W., Kistner, E.O., Courchesne, E., Cox, N.J., Cook, E.H. Jr, Macdonald, R.L., Sutcliffe, J.S. Maternal transmission of a rare GABRB3 signal peptide variant is associated with autism. Molecular Psychiatry. 16(1):86-96, 2011.
Pierce, K. Early functional brain development in autism and the promise of sleep fMRI. Brain Research, 1380:162-74, 2011.
2000s
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2010 |
Morgan, J.T., Chana, G., Pardo, C.A., Achim, C., Semendeferi, K., Buckwalter, J., Courchesne, E., Everall, I.P. Microglial Activation and Increased Microglial Density Observed in the Dorsolateral Prefrontal Cortex in Autism. Biological Psychiatry, 15;68(4):368-376, 2010. Schumann, C.M., Bloss, C.S., Barnes, C.C., Wideman, G.M., Carper, R.A., Akshoomoff, N., Pierce, K., Hagler, D., Schork, N., Lord, C., Courchesne, E. Longitudinal magnetic resonance imaging study of cortical development through early childhood in autism. Journal of Neuroscience, 30(12):4419-27, 2010. |
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2009 |
Luyster, R., Gotham, K., Guthrie, W., Coffing, M., Petrak, R., DiLavore, P., Pierce, K., Bishop, S., Esler, A., Hus, V., Richler, J., Risi, S., and Lord, C. Autism Diagnostic Observation Schedule Toddler Module: A new module of a standardized diagnostic measure for autism spectrum disorders. Journal Autism Developmental Disorders. 39(9)1305-1320, 2009. Schumann, C., Barnes, C., Lord, C., Courchesne, E. Amygdala Enlargement in Toddlers with Autism Related to Severity of Social and Communication Impairments. Biological Psychiatry, 66(10):942-949, 2009, |
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2008 |
Morgan, J., Chana, G., Buckwalter, J., Courchesne, E., Everall, I. Increased Iba-1 positive microglial cell density in the autistic brain. Biological Psychiatry, 63(7):197S-197S, 2008. Morgan, J., Chana, G., Buckwalter, J., Courchesne, E., Everall, I. Increased Iba-1 positive microglial cell density in the autistic brain. Biological Psychiatry, 63(7):197S-197S, 2008.Redcay, E., Haist, F., Courchesne, E. Functional neuroimaging of speech perception during pivotal period in language acquisition. Developmental Science, 11(2):237-52, 2008.Kim, S., Brune, C., Kistner, E., Christian, S., Courchesne, E., Cox, N., Cook, E. Transmission disequilibrium testing of the chromosome 15q11-q13 region in autism. American Journal of Medical Genetics Neuropsychiatry, 147B(7):1116-25, 2008. Kleinhans, N., Muller, R., Cohen, D., Courchesne, E. Atypical functional lateralization of language in autism spectrum disorders. Brain Research, 1221:115-125, 2008
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2007 |
Gaffrey, M.S., Kleinhans, N.M., Haist, F., Akshoomoff, N., Campbell, A., Courchesne, E., Muller, R.A. A typical participation of visual cortex during word processing in autism: An fMRI study of semantic decision. Neuropsychologia, 45(8):1672-84, 2007. Epub 2007 Jan 16. Belmonte, M.K., Mazziotta, J.C., Minshew, N.J., Evans, A.C., Courchesne, E., Dager, S.R., Bookheimer, S.Y., Aylward, E.H., Amaral, D.G., Cantor, R.M., Chugani, D.C., Dale, A.M., Davatzikos, C., Gerig, G., Herbert, M.R., Lainhart, J.E., Murphy, D.G., Piven, J., Reiss, A.L., Schultz, R.T., Zeffiro, T.A., Levi-Pearl, S., Lajonchere, C., Colamarino, S.A. Offering to Share: How to Put Heads Together in Autism Neuroimaging. Journal of Autism Developmental Disorders, 38(1):2-13, 2008. |
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2006 |
Kennedy, D.P., Redcay, E., Courchesne, E. Failing to deactivate: resting functional abnormalities in autism. Proceedings of the National Academy of Sciences U S A, 103(21):8275-80, 2006. Epub 2006 May 15. DiCicco-Bloom, E., Lord, C., Zwaigenbaum, L., Courchesne, E., Dager, S.R., Schmitz, C., Schultz, R.T., Crawley, J., Young, L.J. The developmental neurobiology of autism spectrum disorder. Journal of Neuroscience, 26(26):6897-906, 2006. Review. |
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2005 |
Carper, R.A. and Courchesne, E. Localized enlargement of the frontal cortex in early autism. Biological Psychiatry, 57:126-133, 2005. Haist, F., Adamo, M., Westerfield, M., Courchesne, E., Townsend, J. The functional neuroanatomy of spatial attention in autism spectrum disorder. Developmental Neuropsychology, 27(3):425-58, 2005. |
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2004 |
Pierce, K., Haist, F., Sedaghat, F., & Courchesne, E., 2004. The brain response to personally familiar faces in autism: findings of fusiform activity and beyond. Brain, 2004 127(Pt 12):2703-16. Akshoomoff, N., Lord, C., Lincoln, A.J., Courchesne, R.Y., Carper, R.A., Townsend, J., Courchesne, E. Outcome classification of preschool children with autism spectrum disorders using MRI brain measures. Journal of the American Academy of Child Adolescent Psychiatry, 43(3):349-357, 2004. A |
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2003 |
Muller, R-A., Kleinhans, N., Kemmotsu, N., Pierce, K., Courchesne, E. Abnormal variability and distribution of functional maps in autism: an fMRI study of visuomotor learning. American Journal of Psychiatry, 160(10):1847-62, 2003. Allen, G. And Courchesne, E. Differential effects of developmental cerebellar abnormality on cognitive and motor functions in the cerebellum: An fMRI study of autism. American Journal of Psychiatry, 160(2):262-273, 2003. Courchesne, E., Bartholomeusz, H.H., Karns, C.M., Townsend, J. MRI evidence of increased brain size in young children but not adults with autism. Biological Psychiatry, Accepted Pending Revision 4/4/03. Courchesne, E., Carper, R., Akshoomoff, N. Evidence of brain overgrowth in the first year of life in autism. Journal of the American Medical Association, 290(3):337-344, 2003. Muller, R.A., Kleinhans, N., Courchesne, E. Linguistic theory and neuroimaging evidence: an fMRI study of Broca’s area in lexical semantics. Neuropsychologia. 41(9):1199-207, 2003. |
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2002 |
Makeig, S, Westerfield, M, Jung, T-P, Enghoff, S, Townsend, J, Courchesne, E, Sejnowski, TJ. Dynamic brain sources of visual evoked responses. Science, 295(5555), 690-694, 2002. Carper, R.A., Moses, P., Tigue, Z.D., Courchesne, E. Cerebral lobes in autism: Early hyperplasia and abnormal age effects. NeuroImage, 16:1038-51, 2002. Akshoomoff, N., Pierce, K., Courchesne, E. The neurobiological basis of autism from a developmental perspective. Development and Psychopathology, 14:613-634, 2002. Bartholomeusz, H.H., Courchesne, E., and Karns, C. Relationship between head circumference and brain volume in healthy normal children and adults. Neuropediatrics, 33:239-41, 2002. Kim, S.J., Herzing, L.B., Veenstra-VanderWeele, J., Lord, C., Courchesne, R., Leventhal, B.L., Ledbetter, D.H., Courchesne, E., Cook, Jr., E.H. Mutation screening and transmission disequilibrium study of ATP10C in autism. American Journal of Medical Genetics, 114(2):137-43, 2002. Muller, R.A., Kleinhans, N., Pierce, K., Kemmotsu, N., Courchesne, E. Functional MRI of motor sequence acquisition: effects of learning stage and performance. Cognitive Brain Research, 14(2):277-93, 2002. Jones, W., Hesselink, J., Courchesne, E., Duncan, T., Matsuda, K., Bellugi, U. Cerebellar abnormalities in infants and toddlers with Williams syndrome. Developmental Medicine and Child Neurology, 44(10):688-94, 2002. Courchesne, E. Abnormal early brain development in autism. Molecular Psychiatry, 7:S21-S23, 2002. Müller, R.-A., Pierce, K., Kleinhans, N., Kemmotsu, N. & Courchesne, E. Functional MRI of motor sequence learning: effects of learning stage and performance. Cognitive Brain Research, 14:277-293, 2002. Kim, S-J., Young, L. J., Gonen, D, , Veenstra-Vanderweele, J., Courchesne, R.Y., Courchesne, E., Lord, C., Leventhal, B.L., Cook, Jr., E.H., Insel, T.R. Transmission disequilibrium testing of arginine vasopressin receptor 1A (AVPR1A) polymorphisms in Autism. Molecular Psychiatry, 7:502-507, 2002. Veenstra-VanderWeele, J., Kim, S-J, Lord, C., Courchesne, R., Akshoomoff, N., Leventhal, B.L., Courchesne, E., and Cook, E.H. Transmission disequilibrium studies of the serotonin 5-HT2A receptor gene (HTR2A) in autism. American Journal of Medical Genetics (Neuropsychiatric Genetics) 114:277-283, 2002. Bartholomeusz, H.H., Courchesne, E., Karns, C. Relationship between head circumference and brain volume in healthy normal children and adults. Neuropediatrics, 33:239-241, 2002. Courchesne, E. and Pierce, K. Autism. In V.S. Ramachandran (Editor), Encyclopedia of the Human Brain, Volume 1, Academic Press, San Diego, CA, 2002. Pierce, K. And Courchesne, E. Autism. Encyclopedia of Cognitive Science MacMillan, Hampshire UK, L. Nadel (editor), pp.278-283, 2002. |
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2001 |
Pierce, K., Muller, R.A., Ambrose, J., Allen, G., Courchesne, E. Face processing occurs outside the fusiform ‘face area’ in autism: Evidence from functional MRI. Brain, 124:2059-2073, 2001. Allen, G. And Courchesne, E. Attention function and dysfunction in autism. Frontiers in Bioscience, 6:d105-119, 2001. Kim, S-J, Cox, N., Courchesne, R., Lord, C., Corsello, C., Akshoomoff, N., Guter, S., Leventhal, B.L., Courchesne, E., and Cook, E.H. Transmission disequilibrium mapping at the serotonin transporter gene (SLC6A4) region in autistic disorder. Molecular Psychiatry. 7:278-288, 2001. Jung, T.P., Makeig, S., Westerfield, M., Townsend, J., Courchesne, E., Sejnowski, T.J. Analysis and visualization of single-trial event-related potentials. Human Brain Mapping, 14(3):166-85, 2001. Courchesne, E., Karns, C., Davis, H.R., Ziccardi, R., Tigue, Z., Pierce, K., Moses, P., Chisum, H.J., Lord, C., Lincoln, A.J., Pizzo, S., Schreibman, L., Haas, R.H., Akshoomoff, N., Courchesne, R.Y. Unusual brain growth patterns in early life in patients with autistic disorder: An MRI study. Neurology, 57:245-254, 2001. Muller, R-A., Pierce, K., Ambrose, J.B., Allen, G., Courchesne, E. Atypical patterns of cerebral motor activation in autism: a functional magnetic resonance study. Biological Psychiatry, 49:665-676, 2001. Pierce, K., Courchesne, E. Evidence for a cerebellar role in reduced exploration and stereotyped behavior in autism. Biological Psychiatry, 49:655-664, 2001. Saitoh, O., Karns, C., Courchesne, E. Development of the hippocampal formation from 2 to 42 years: MRI evidence of smaller area dentata in autism. Brain, 124:1317-1324, 2001. Moses, P., Courchesne, E., Stiles, J., Trauner, D., Egaas, B., Edwards, E. Regional size reduction in the Human corpus callosum following pre- and perinatal brain injury. Cerebral Cortex, 10:1200-1210, 2000. Townsend, J., Westerfield, M., Leaver, E., Makeig, S., Jung, T-P., Pierce, K., Courchesne, E. Event-related brain response abnormalities in autism: evidence for impaired cerebello-frontal spatial attention networks. Cognitive Brain Research, 11(1), 127-145. 2001. Muller, R-A., Kleinhans, N., Courchesne, E. Broca’s area and the discrimination of frequency transitions: a functional MRI study. Brain and Language, 76:70-76, 2001. Juul-Dam, N., Townsend, J., Courchesne, E. Prenatal, perinatal, and neonatal factors in autism, PDD-NOS, and the general population. Pediatrics, 107(4):e63, 2001. |
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2000 |
Courchesne, E. And Pierce, K. An inside look at the neurobiology, etiology, and future research of autism. Advocate, pp.18-22, 2000. Jung, T-P., Makeig, S., Westerfield, M., Townsend, J., Courchesne, E., Sejnowski, T.J. Removal of eye activity artifacts from visual event-related potentials in normal and clinical subjects. Clinical Neurophysiology, 111:1745-1758, 2000. Courchesne, E., Chisum, H.J., Townsend, J., Cowles, A., Covington, J., Egaas, B., Harwood, M., Hinds, S., Press, G.A. Normal brain development and aging: Quantitative analysis at in vivo MR imaging in healthy volunteers. Radiology, 216:672-682, 2000. Jung, T-P., Makeig, S., Westerfield, M., Townsend, J., Courchesne, E., and Sejnowski, T.J. Blind source separation of single-trial event-related potentials in a visual spatial attention task. IEEE Transactions on Biomedical Engineering. In press, 2000. Carper, R.A. and Courchesne, E. Inverse correlation between frontal lobe and cerebellum sizes in children with autism. Brain, 123:836-844, 2000. Graf, W.D., Marin-Garcia, J., Gao, H.G., Pizzo, S., Naviaux, R.K., Markusic, B.S., Barshop, B.A., Courchesne, E., Haas, R.H. Autism associated with the mtDNA G8363A tRNAlys mutation. Journal of Child Neurology, 15:357-361, 2000. Pierce, K. and Courchesne, E. Exploring the neurofunctional organization of face processing in autism. Archives of General Psychiatry, 57:344-345, 2000. |
1990s
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1999 |
Courchesne, E. and Yeung-Courchesne, R, and Pierce, K. Biological and behavioral heterogeneity in autism: Role of pleiotropy and epigenesis. In: S.H. Broman and J.M. Fletcher (Eds.) The Changing Nervous System: Neurobehavioral Consequences of Early Brain Disorders. New York: Oxford University Press, pp. 292-338, 1999. Courchesne, E. An MRI study of autism: The cerebellum revisited. Neurology, 52:1106, 1999. Harris, N.S., Courchesne, E., Townsend, J., Carper, R.A. and Lord, C. Neuroanatomic contributions to slowed orienting of attention in children with autism. Cognitive Brain Research, 8:61-71, 1999. Courchesne, E., Müller, R.-A. and Saitoh, O. Brain weight in autism: Normal in the majority of cases, megalencephalic in rare cases. Neurology, 52:1057-1059. 1999. Makeig, S., Westerfield, M., Jung, T-P, Covington, J., Townsend, J., Sejnowski, T. and Courchesne, E. Functionally independent components of late positive event-related potential during visual spatial attention. Journal of Neuroscience, 19(7), 2665-80, 1999. Townsend, J., Courchesne, E., Covington, J., Westerfield, M., Harris, N.S., Lyden, P., Lowry, T.P. and Press, G.A. Spatial attention deficits in patients with acquired or developmental cerebellar abnormality. Journal of Neuroscience,19(13):5632-5643, 1999. Jung, T-P, Makeig, S., Westerfield, M., Townsend, J., Courchesne, E., and Sejnowski, T.J. Analyzing and visualizing single-trial event-related potentials. Advances in Neural Information Processing Systems, 11:118-124, 1999. Makeig, S., Westerfield, M., Townsend, J., Jung, T-P., Courchesne, E., and Sejnowski, T.J. Functionally independent components of early event-related potentials in a visual spatial attention task. Philosophical Transactions: Biological Sciences, 354:(1387):1135-1144, 1999. Jung, T-P., Makeig, S., Westerfield, M., Townsend, J., Courchesne, E., and Sejnowski, T.J. Independent component analysis of single-trial event-related potentials. 1St Int’l Workshop on Independent Component Analysis and Signal Separation, 173-178, 1999. Lassig, J.P., Vachirasomtoon, K., Hartzell, K., Leventhal, M., Courchesne, E., Courchesne, R., Lord, C., Leventhal, B.L., Cook, Jr., E.H. Physical mapping of the serotonin 5-HT7 receptor gene (HTR7) to chromosome 10 and pseudogene (HTR7P) to chromosome 12, and testing of linkage disequilibrium between HTR7 and autistic disorder. American Journal of Medical Genetics (Neuropsychiatric Genetics), 88:472-475, 1999. |
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1998 |
Allen, G. and Courchesne, E. The cerebellum and non-motor function: Clinical implications. Molecular Psychiatry, 3:207-210, 1998. Lincoln, A., Courchesne, E., Allen, M., Hanson, E. and Ene, Michaela. Neurobiology of asperger syndrome: Seven case studies and quantitative magnetic resonance imaging findings. In: E. Schopler, G. Mesibov and Kunce (Eds.) Asperger Syndrome or High Functioning Autism? New York: Plenum Press, 1998. Cook. Jr., E.H., Courchesne, R.Y., Cox, N.J., Lord, C., Gonen, D., Guter, S.J., Lincoln, A., Nix, K., Haas, R., Leventhal, B.L. and Courchesne, E. Linkage disequilibrium mapping with 15q11-13 markers in autistic disorder. The American Journal of Human Genetics, 62:1077-1083, 1998. Müller, R.-A. and Courchesne, E. The duplicity of plasticity: A conceptual approach to the study of early lesions and developmental disorders. In: M. Ernst and J. Rumsey (Eds.) The Foundation and Future of Functional Neuroimaging in Child Psychiatry, New York: Cambridge University Press, 1998. Müller, R.-A., Courchesne, E. and Allen, G. The cerebellum: So much more. Science, 282:879 880, 1998. (Letter) |
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1997 |
Courchesne, E. Brain: early sensory experience on neural structural development. In: S. Parker (Ed. in Chief), 1997 McGraw-Hill Yearbook of Science and Technology, supplement to Encyclopedia of Science and Technology. McGraw-Hill Inc.: New York, pp. 57-58, 1997. Courchesne, E. and Plante, E. Measurement and analysis issues in neurodevelopmental MR imaging. In: R.W. Thatcher, G.R. Lyon, J. Rumsey and N. Krasnegor (Eds.), Developmental Neuroimaging: Mapping the Development of Brain and Behavior. Academic Press: New York, pp. 43-65, 1997. Courchesne, E. Brainstem, cerebellar and limbic neuroanatomical abnormalities in autism. Current Opinion in Neurobiology, 7:269-278, 1997. Yeung-Courchesne, R. and Courchesne, E. From impasse to insight in autism research: From behavioral symptoms to biological explanations. Development and Psychopathology, 9:389-419, 1997. Allen, G., Buxton, R.B., Wong, E.C. and Courchesne, E. Attentional activation of the cerebellum independent of motor involvement. Science, 275:1940-1943, 1997. Courchesne, E. Prediction and preparation: Anticipatory role of the cerebellum in diverse neurobehavioral functions. Behavioral and Brain Sciences, 20:248-249, 1997. Courchesne, E. and Allen, G. Prediction and preparation, fundamental functions of the cerebellum. Learning and Memory, 4:1-35, 1997. Akshoomoff, N.A., Courchesne, E. and Townsend, J. Attention coordination and anticipatory control. In: J.D. Schmahmann (Ed.), The Cerebellum and Cognition, International Review of Neurobiology, Vol. 41. Academic Press: San Diego, pp. 575-598, 1997. Cook, Jr., E.H., Lindgren, V., Leventhal, B.L., Courchesne, R., Lincoln, A., Shulman, C., Lord, C. and Courchesne, E. Autism or atypical autism in maternally but not paternally derived proximal 15q duplication. American Journal of Human Genetics, 60:928-934, 1997. Cook, Jr., E.H., Courchesne, R., Lord, C., Cox , N., Yan, S., Lincoln, A., Haas, R., Courchesne, E. and Leventhal, B.L. Evidence of linkage between the serotonin transporter and autistic disorder. Molecular Psychiatry, 2:247-250, 1997. Saitoh, O. and Courchesne, E. MRI study of the brain in autism. Psychiatry and Clinical Neurosciences, 52:S219-S222, 1997. |
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1996 |
Townsend, J., Courchesne, E. and Egaas, B. Slowed orienting of covert visual-spatial attention in autism: Specific deficits associated with cerebellar and parietal abnormality. Development and Psychopathology, 8:563-584, 1996. Townsend, J., Singer Harris, N. and Courchesne, E. Visual attention abnormalities in autism: Delayed orienting to location. Journal of the International Neuropsychological Society, 2:541-550, 1996. Haas, R.H., Townsend, J., Courchesne, E., Lincoln, A.J., Schreibman, L. and Yeung-Courchesne, R. Neurologic abnormalities in infantile autism. Journal of Child Neurology, 11:84-92, 1996. |
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1995 |
Saitoh, O., Courchesne, E., Egaas, B., Lincoln, A.J. and Schreibman, L. Cross-sectional area of the posterior hippocampus in autistic patients with cerebellar and corpus callosum abnormalities. Neurology, 45:317-324, 1995. Courchesne, E., Akshoomoff, N.A., Townsend, J. and Saitoh, O. A model system for the study of attention and the cerebellum: Infantile autism. In: G. Karmos, M. Molnar, V. Csépe, I. Czigler, and J.E. Desmedt (Eds.), Perspectives of Event-Related Potentials Research (EEG Suppl. 44), Amsterdam: Elsevier Science B.V., pp. 315-325, 1995. Egaas, B., Courchesne, E. and Saitoh, O. Reduced size of corpus callosum in autism. Archives of Neurology, 52:794-801, 1995. Courchesne, E. New evidence of cerebellar and brainstem hypoplasia in autistic infants, children and adolescents: The MR imaging study by Hashimoto and colleagues. Journal of Autism and Developmental Disorders, 25:19-22, 1995. Belmonte, M., Egaas, B., Townsend, J. and Courchesne, E. NMR intensity of corpus callosum differs with age but not with diagnosis of autism. NeuroReport, 6:1253-1256, 1995. Lincoln, A.J., Courchesne, E., Harms, L. and Allen, M. Sensory modulation of auditory stimuli in children with autism and receptive developmental language disorder: Event-related brain potential evidence. Journal of Autism and Developmental Disorders, 25:521-539, 1995. Courchesne, E. Infantile autism. Part 1: MR imaging abnormalities and their neurobehavioral correlates. International Pediatrics, 10:141-154, 1995. Courchesne, E. Infantile autism. Part 2: A new neurodevelopmental model. International Pediatrics, 10:155-165, 1995. |
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1994 |
Courchesne, E., Townsend, J.P., Akshoomoff, N.A., Yeung-Courchesne, R., Press, G.A., Murakami, J.W., Lincoln, A.J., James, H.E., Saitoh, O., Egaas, B., Haas, R.H., and Schreibman, L. A new finding: Impairment in shifting attention in autistic and cerebellar patients. In: S.H. Broman and J. Grafman (Eds.), Atypical Cognitive Deficits in Developmental Disorders: Implications for Brain Function. Lawrence Erlbaum: New Jersey, pp. 101-137, 1994. Courchesne, E., Saitoh, O., Yeung-Courchesne, R., Press, G.A. Lincoln, A.J., Haas, R.H. and Schreibman, L. Abnormality of cerebellar vermian lobules VI and VII in patients with infantile autism: Identification of hypoplastic and hyperplastic subgroups with MR imaging. American Journal of Roentgenology, 162:123-130, 1994. Courchesne, E., Townsend, J. and Saitoh, O. The brain in infantile autism: Posterior fossa structures are abnormal. Neurology, 44:214-223, 1994. Courchesne, E., Yeung-Courchesne, R. and Egaas, B. Methodology in neuroanatomic measurement. Neurology, 44:203-208, 1994. Courchesne, E., Saitoh, O., Townsend, J.P., Yeung-Courchesne, R.,Press, G.A., Lincoln, A.J., Haas, R.H. and Schreibman, L. Cerebellar hypoplasia and hyperplasia in infantile autism. The Lancet, 343:63-64, 1994. Courchesne, E., Townsend, J. and Chase, C. Neurodevelopmental principles guide research on developmental psychopathologies. In: D. Cicchetti and D. Cohen (Eds.), A Manual of Developmental Psychopathology, New York: John Wiley, pp. 195-226, 1994. Townsend, J. and Courchesne, E. Parietal damage and narrow “spotlight” spatial attention. Journal of Cognitive Neuroscience, 6:220-232, 1994. Akshoomoff, N.A. and Courchesne, E. ERP evidence for a shifting attention deficit in patients with damage to the cerebellum. Journal of Cognitive Neuroscience, 6:388-399, 1994. Courchesne, E., Chisum, H. and Townsend, J. Neural activity-dependent brain changes in development: Implications for psychopathology. Development and Psychopathology, 6:697-722, 1994. Courchesne, E., Townsend, J., Akshoomoff, N.A., Saitoh, O., Yeung-Courchesne, R., Lincoln, A.J., James, H.E., Haas, R.H., Schreibman, L. and Lau, L. Impairment in shifting attention in autistic and cerebellar patients. Behavioral Neuroscience, 108:848-865, 1994. |
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1993 |
Courchesne, E., Press, G.A. and Yeung-Courchesne, R. Parietal lobe abnormalities detected with MR in patients with infantile autism. American Journal of Roentgenology, 160:387-393, 1993. Lincoln, A.J., Courchesne, E., Harms, L. and Allen, M. Contextual probability evaluation in autistic, receptive developmental language disorder, and control children: Event-related potential evidence. Journal of Autism and Developmental Disorders, 23:37-58, 1993. |
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1992 |
Courchesne, E. Autism. In: E. Peschel, R. Peschel, C.W. Howe and J.W. Howe (Eds.), Neurobiological Disorders in Children & Adolescents: A Guide to Research & Policy on Schizophrenia, Bipolar Disorder, Autism & More for Professionals & Families. Jossey-Bass: San Francisco, 1992. Murakami, J.W., Courchesne, E., Haas, R.H., Press, G.A. and Yeung-Courchesne, R. Cerebellar and cerebral abnormalities in Rett syndrome: A quantitative MR analysis. American Journal of Roentgenology, 159:177-183, 1992. Press, G.A. and Courchesne, E. Atlas of cerebellar hemispheres and vermis. In: L.A. Hyman and V.C. Hinck (Eds.), Clinical Brain Imaging: Normal Structure and Functional Anatomy. Mosby Yearbook Publishers Inc., pp. 251-279, 1992. Press, G.A. and Courchesne, E. Cerebellar hemispheres and vermis. In: L.A. Hyman and V.C. Hinck (Eds.), Clinical Brain Imaging: Normal Structure and Functional Anatomy. Mosby Yearbook Publishers Inc., pp. 281-286, 1992. Akshoomoff, N.A., Courchesne, E., Press, G.A. and Iragui, V. Contribution of the cerebellum to neuropsychological functioning: Evidence from a case of cerebellar degenerative disorder. Neuropsychologia, 30:315-328, 1992. Akshoomoff, N.A. and Courchesne, E. A new role for the cerebellum in cognitive operations. Behavioral Neuroscience, 106:731-738, 1992. Courchesne, E., Akshoomoff, N.A. and Townsend, J. Recent advances in autism. In: H. Naruse and E.M. Ornitz (Eds.), Neurobiology of Infantile Autism. Elsevier Science Publishers B.V., pp. 111-128, 1992. Lincoln, A.J., Dickstein, P., Courchesne, E., Elmasian, R. and Tallal, P. Auditory processing abilities in non-retarded adolescents and young adults with developmental receptive language disorder and autism. Brain and Language, 43:613-622, 1992. Clark, V.P., Courchesne, E. and Grafe, M. In vivo myeloarchitectonic analysis of human striate and extrastriate cortex using magnetic resonance imaging. Cerebral Cortex, 2:417-424, 1992. |
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1991 |
Courchesne, E. Chronology of postnatal human brain development: Event-related potential, positron emission tomography, myelinogenesis, and synaptogenesis studies. In: J.W. Rohrbaugh, R. Parasuraman and R. Johnson (Eds.), Event-Related Brain Potentials: Basic Issues and Applications. Oxford Press: New York, pp. 210-241, 1990., C., Ameli, R., Courchesne, E. and Braff, D.L. Effects of task relevance and attention on P3 in schizophrenic patients. Schizophrenia Research, 4:11-21, 1991. Courchesne, E. Neuroanatomic imaging in autism. Pediatrics, 87:781-790, 1991. Hsu, M., Yeung-Courchesne, R., Courchesne, E. and Press, G.A. Absence of magnetic resonance imaging evidence of pontine abnormality in infantile autism. Archives of Neurology, 48:1160-1163, 1991. Epstein, C.J., Korenberg, J.R., Annerén, G., Antonarakis, S.E., Aymé, S., Courchesne, E., Epstein, L.B., Fowler, A., Groner, Y., Huret, J.L., Kemper, T.L., Lott, I.T., Lubin, B.H., Magenis, E., Opitz, J.M., Patterson, D., Priest, J.H., Pueschel, S.M., Rapoport, S.I., Sinet, P.-M., Tanzi, R.E. and de la Cruz, F. Protocols to establish genotype-phenotype correlations in Down syndrome. American Journal of Human Genetics, 49:207-235, 1991. |
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1990 |
Grillon, C., Courchesne, E., Ameli, R., Elmasian, R. and Braff, D. Effects of rare non-target stimuli on brain electrophysiological activity and performance. International Journal of Psychophysiology, 9:257-267, 1990. Press, G.A., Murakami, J.W., Courchesne, E., Grafe, M. and Hesselink, J.R. The cerebellum: 3. Anatomic-MR correlation in the coronal plane. American Journal of Roentgenology, 154(3):593-602, 1990 the coronal plane. American Journal of Neuroradiology, 11:41-50, 1990. (Also published in the March 1990 issue of American Journal of Roentgenology.) Courchesne, E., Akshoomoff, N.A. and Townsend, J. Recent advances in autism. Current Opinions in Pediatrics, 2:685-693,1990. Lincoln, A.J., Courchesne, E., and Elmasian, R. Considerations for the study of event-related brain potentials and developmental psychopathology. In: A. Rothenberger (Ed.), Brain and Behavior in Child Psychiatry. Springer-Verlag: New York, pp. 16-33, 1990. Grillon, C., Courchesne, E., Ameli, R., Geyer, M.A. and Braff, D.L. Increased distractibility in schizophrenic patients: Electrophysiologic and behavioral evidence. Archives of General Psychiatry, 47:171-179, 1990. |
1980s
Courchesne, E. Neuroanatomical systems involved in infantile autism: The implications of cerebellar abnormalities. In: G. Dawson (Ed.), Autism: New Perspectives on Diagnosis, Nature and Treatment. The Guilford Press: New York, pp. 119-143, 1989.
Courchesne, E., Press, G.A., Murakami, J., Berthoty, D., Grafe, M., Wiley, C.A. and Hesselink, J.R. The cerebellum in sagittal plane-- Anatomic-MR correlation: 1. The vermis. American Journal of Neuroradiology, 10:659-665, 1989. (Also published in the October 1989 issue of American Journal of Roentgenology.)
Press, G.A., Murakami, J., Courchesne, E., Berthoty, D.P., Grafe, M., Wiley, C.A. and Hesselink, J.R. The cerebellum in sagittal plane--Anatomic-MR correlation: 2. The cerebellar hemispheres. American Journal of Neuroradiology, 10:667-676, 1989. (Also published in the October 1989 issue of American Journal of Roentgenology.)
Murakami, J.W., Courchesne, E., Press, G.A., Yeung-Courchesne, R. and Hesselink, J.R. Reduced cerebellar hemisphere size and its relationship to vermal hypoplasia in autism. Archives of Neurology, 46:689-694, 1989.
Courchesne, E., Lincoln, A.J., Yeung-Courchesne, R., Elmasian, R. and Grillon, C. Pathophysiologic findings in non-retarded autism and receptive developmental language disorder. Journal of Autism and Developmental Disorders, 19:1-17, 1989.
Grillon, C., Courchesne, E. and Akshoomoff, N. Brainstem and middle latency auditory evoked potentials in autism and developmental language disorder. Journal of Autism and Developmental Disorders, 19:255-269, 1989.
Ameli, R., Courchesne, E., Lincoln, A., Kaufman, A.S. and Grillon, C. Visual memory processes in high-functioning individuals with autism. Journal of Autism and Developmental Disorders, 18:601-615, 1988.
Lincoln, A.J., Courchesne, E., Kilman, B.A., Elmasian, R. and Allen, M. A study of intellectual abilities in high-functioning people with autism. Journal of Autism and Developmental Disorders, 18:505-524, 1988.
Courchesne, E. Physioanatomical considerations in Down syndrome. In: L. Nadel (Ed.), The Psychobiology of Down Syndrome. MIT Press: Cambridge, MA, pp. 291-313, 1988.
Courchesne, E. Cerebellar changes in autism. In: J. Swann and A. Messer (Eds.), Disorders of the Developing Nervous System: Changing Views on Their Origins, Diagnoses and Treatments. Alan R. Liss, Inc.: New York, pp. 93-109, 1988.
Courchesne, E., Yeung-Courchesne, R., Press, G.A., Hesselink, J.R. and Jernigan, T.L. Hypoplasia of cerebellar vermal lobules VI and VII in autism. The New England Journal of Medicine, 318:1349-1354, 1988.
Courchesne, E. A neurophysiological view of autism. In: E. Schopler and G.B. Mesibov (Eds.), Neurobiological Issues in Autism. Plenum Press: New York, pp. 285-324, 1987.
Courchesne, E., Elmasian, R. and Yeung-Courchesne, R. Electrophysiological correlates of cognitive processing: P3b and Nc, basic, clinical, and developmental research. In: A.M. Halliday, S.R. Butler and R. Paul (Eds.), A Textbook of Clinical Neurophysiology, John Wiley and Sons Ltd.: Sussex, pp. 645-676, 1987.
Courchesne, E., Hesselink, J.R., Jernigan, T.L. and Yeung-Courchesne, R. Abnormal neuroanatomy in a nonretarded person with autism: Unusual findings with magnetic resonance imaging. Archives of Neurology, 44:335-341, 1987.
Courchesne, E. and Yeung-Courchesne, R. Event-related brain potentials. In: M. Rutter, A. Hussain Tuma and I.S. Lann (Eds.), Assessment and Diagnosis in Child Psychopathology. Guilford Press: New York, pp. 264-299, 1987.
Woods, D.L. and Courchesne, E. Intersubject variability elucidates the cerebral generators and psychological correlates of ERPs. In: R. Johnson, Jr., J.W. Rohrbaugh and R. Parasuraman (Eds.), Current Trends in Event-Related Potential Research (EEG Suppl. 40) Elsevier Science Publishers B.V.: New York, pp. 293-299, 1987.
Adams, J., Courchesne, E., Elmasian, R. and Lincoln, A. Increased amplitude of the auditory P2 and P3b components in adolescents with developmental dysphasia. In: R. Johnson, Jr., R. Parasuraman and J.W. Rohrbaugh (Eds.), Current Trends in Event-Related Potential Research (EEG Suppl. 40). Elsevier Science Publishers B.V.: New York, pp. 577-583, 1987.
Lincoln, A.J., Courchesne, E., Elmasian, R. Hypothesis testing with principal components analysis: The dissociation of P3b and Nc. In: R. Johnson, Jr., J.W. Rohrbaugh and R. Parasuraman (Eds.), Current Trends in Event-Related Potential Research (EEG Suppl. 40) Elsevier Science Publishers B.V.: New York, pp. 211-219, 1987.
Woods, D.L. and Courchesne, E. The recovery functions of auditory event-related potentials during split-second discriminations. Electroencephalography and Clinical Neurophysiology, 65:304-15, 1986. Electroencephalography and Clinical Neurophysiology, 65:304-315, 1986.
Woods, D.L. and Courchesne, E. Event-related potentials during split-second auditory and visual decision making. In: W.C. McCallum, R. Zappoli and F. Denoth (Eds.), Cerebral Psychophysiology: Studies in Event-Related Potentials, (EEG Suppl. 39), 152-154, 1986.
Courchesne, E., Lincoln, A.J., Kilman, B.A. and Galambos, R. Event-related brain potential correlates of the processing of novel visual and auditory information in autism. Journal of Autism and Develop mental Disorders, 15:55-76, 1985.
Lincoln, A.J., Courchesne, E., Kilman, B.A. and Galambos R. Neuropsychological correlates of information-processing by children with Down syndrome. Journal of Mental Deficiency, 89:403-414, 1985.
Courchesne, E., Courchesne, R.Y., Hicks, G. and Lincoln, A.J. Functioning of the brain-stem auditory pathway in non-retarded autistic individuals. Electroencephalography and Clinical Neurophysiology, 61:491-501, 1985.
Akshoomoff, N., Courchesne, E., Yeung-Courchesne, R. and Costello, J. Brainstem auditory evoked potentials in receptive developmental language disorder. Brain and Language, 37:409-418, 1989.
Kurtzberg, D., Vaughan, Jr., H.G., Courchesne, E., Friedman, D., Harter, M.R. and Putnam, L.E. Developmental aspects of event-related potentials. In: R. Karrer, J. Cohen and P. Tueting (Eds.), Brain and Information Event-related Potentials, Vol. 425. The New York Academy of Sciences: New York, pp. 300-318, 1984.
Courchesne, E., Kilman, B.A., Galambos, R. and Lincoln, A.L. Autism: Processing of novel auditory information assessed by event-related brain potentials. Electroencephalography and Clinical Neurophysiology. 59:238-248, 1984.
Courchesne, E. A critical review of the use of ERP’s for studying developmental psychopathologies. Center for Studies of Child and Adolescent Psychopathology, Clinical Research Branch, National Institutes of Mental Health, 1984.
Courchesne, E. Cognitive components of the event-related brain potential: Changes associated with development. In: A.W.K. Gaillard and W. Ritter (Eds.), Tutorials in Event-Related Potential Research: Endogenous Components. North-Holland Publishing Co.: Amsterdam, pp. 329-344, 1983.
Courchesne, E., Ganz, L. and Norcia, A.M. Event-related brain potentials to human faces in infants. Child Development, 52:804-811, 1981.
Woods, D.L., Courchesne, E., Hillyard, S.A. and Galambos, R. Split-second recovery of the P3 component in multiple decision tasks. In: H.H. Kornhuber and L. Deecke (Eds.). Progress in Brain Research. Vol. 54: Motivation, Motor and Sensory Processes of the Brain. Elsevier/North-Holland Biomedical Press: Amsterdam, pp. 322-330, 1980.
Woods, D.L., Hillyard, S.A., Courchesne, E. and Galambos, R. Electrophysiological signs of split-second decision making. Science. 207:655-657, 1980.
Woods, D.L., Courchesne, E., Hillyard, S.A. and Galambos, R. Recovery cycles of event-related potentials in multipledetection tasks. Electroencephalography and Clinical Neurophysiology, 50:335-347, 1980.
1970s
Courchesne, E. From infancy to adulthood: The neurophysiological correlates of cognition. In: J.E. Desmedt (Ed.), Progress in Clinical Neurophysiology. Volume 6: Cognitive Components in Event-Related Cerebral Potentials. Karger Publishing: New York, pp. 224-242, 1979.
Campbell, K.B., Courchesne, E., Picton, T.W. and Squires, K.C. Evoked potential correlates of human information processing. Biological Psychology, 8:45-68, 1979.
Courchesne, E. Neurophysiological correlates of cognitive development: Changes in long-latency event-related potentials from childhood to adulthood. Electroencephalography and Clinical Neurophysiology, 45:468-482, 1978.
Courchesne, E. Changes in P3 waves in event repetition: Long-term effects on scalp distribution and amplitude. Electroencephalography and Clinical Neurophysiology, 45:754-766, 1978.
Courchesne, E., Courchesne, R.Y. and Hillyard, S.A. The effect of stimulus deviation on P3 waves to easily recognized stimuli. Neuropsychologia, 16:189-199, 1978.
Courchesne, E., Hillyard, S.A. and Courchesne, R.Y. P3 waves to the discrimination of targets in homogeneous and heterogeneous stimulus sequences. Psychophysiology, 14:590-597, 1977.
Courchesne, E. Event-related brain potentials: Comparison between children and adults. Science. 197:589-592, 1977.
Hillyard, S.A., Courchesne, E., Krausz, H.I. and Picton, T.W. Scalp topography of the P3 wave in different auditory decision tasks. In: W.C. McCallum and J.R. Knott (Eds.). The Responsive Brain. The Proceedings of the Third International Congress on Event-Related Slow Potentials of the Brain. John Wright and Sons Ltd.: Bristol, pp. 81-87, 1976.
Courchesne, E., Hillyard, S.A. and Galambos, R. Stimulus novelty, task relevance and the visual evoked potential in man. Electroencephalography and Clinical Neurophysiology, 39:131-143, 1975.
Courchesne, E. and Barlow, G.W. Effect of isolation on components of aggressive and other behavior in the hermit crab, Pagurus samuelis. Z. vergl. Physiologie. 75:32-48, 1971.