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Vogt KC, et al. Tumor microenvironment-targeted PROTAC nanoparticle self-assembly broadly predicted by structural descriptors. Science Advances 2025; 11(49): eadu2292.
Ross JL et al. Microglia and monocyte-derived macrophages drive progression of pediatric high-grade gliomas and are transcriptionally shaped by histone mutations. Immunity 2024; 57(11): 2669-2687.
Yamada M, et al.. Childhood cancer mutagenesis caused by a domesticated DNA transposase. Science Advances 2024; 10(12): eadn4649.
Koschmann C et al. A road map for the treatment of pediatric diffuse midline glioma. Cancer Cell 2024; 42(1): 1-5.
Tylawsky DE et al. P-selectin-targeted nanocarriers induce active crossing of the blood-brain barrier via caveolin-1-dependent transcytosis. Nature Materials 2023; 22(3):391-399. *corresponding author
This work was highlighted with a Nature Materials News & Views article as well as featured on the NIH Director’s Blog.
News & Views Article: https://www.nature.com/articles/s41563-023-01487-3
NIH Director’s Blog: https://directorsblog.nih.gov/tag/childhood-brain-cancer/