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Department of Neurosciences Department of Neurosciences
The UC San Diego Epilepsy Research Center has multiple research studies that are currently recruiting patients and healthy volunteers participants.

EpiFOS trial: CBD for focal epilepsy

Open-label treatment of focal epilepsy with CBD oil. See patient information brochure or the health care provider information document for referring patients.

ClinicalTrials.gov registration(s): NCT07233239

PI: Taha Gholipour, MD

Sponsor: Jazz Pharmaceuticals

Study website: EpiFOS Clinical Trial

Contact:  EpilepsyCBDstudy@health.ucsd.edu 

Rise trial: new antiseizure medication for focal epilepsy


Randomized Clinical Trial followed by an Open-lebel extension trial. See Brochure for short eligibility description.

ClinicalTrials.gov registration(s): NCT06132893 and NCT06443463

PI: Taha Gholipour, MD

Sponsor: Biohaven Pharmaceuticals

Study website: Rise Clinical Trial

Contact: cbarnet@health.ucsd.edu 

 

Predicting outcomes of epilepsy surgery from individualized resting state fMRI

Current clinical and imaging predictors of response to epilepsy surgery are inadequate, and surgical treatment outcomes are mixed. Predicting the seizure and non-seizure outcomes are critical for clinical decision making. Functional MRI (fMRI) offers noninvasive and accessible means to complement current methods of surgical planning to guide treatment. This project will prospectively collect resting state fMRI from focal epilepsy patients and some healthy volunteers and use new analytic methods to develop predictive models.

Eligible participants: People with focal epilepsy who are undergoing pre-surgical evaluation for open surgery, laser ablation of seizure focus, or placement of neurostimulators. 

UCSD IRB #810686

 PI: Taha Gholipour, MD

Sponsor: National Institute of Neurological Disorders and Stroke 

NIH RePORTER:  K23NS135108

Contact: gholipourlab@ucsd.edu