EpiFOS trial: CBD for focal epilepsy
Open-label treatment of focal epilepsy with CBD oil. See patient information brochure or the health care provider information document for referring patients.
ClinicalTrials.gov registration(s): NCT07233239
PI: Taha Gholipour, MD
Sponsor: Jazz Pharmaceuticals
Study website: EpiFOS Clinical Trial
Contact: EpilepsyCBDstudy@health.ucsd.edu
Rise trial: new antiseizure medication for focal epilepsy
Randomized Clinical Trial followed by an Open-lebel extension trial. See Brochure for short eligibility description.
ClinicalTrials.gov registration(s): NCT06132893 and NCT06443463
PI: Taha Gholipour, MD
Sponsor: Biohaven Pharmaceuticals
Study website: Rise Clinical Trial
Contact: cbarnet@health.ucsd.edu
Predicting outcomes of epilepsy surgery from individualized resting state fMRI
Current clinical and imaging predictors of response to epilepsy surgery are inadequate, and surgical treatment outcomes are mixed. Predicting the seizure and non-seizure outcomes are critical for clinical decision making. Functional MRI (fMRI) offers noninvasive and accessible means to complement current methods of surgical planning to guide treatment. This project will prospectively collect resting state fMRI from focal epilepsy patients and some healthy volunteers and use new analytic methods to develop predictive models.
Eligible participants: People with focal epilepsy who are undergoing pre-surgical evaluation for open surgery, laser ablation of seizure focus, or placement of neurostimulators.
UCSD IRB #810686
PI: Taha Gholipour, MD
Sponsor: National Institute of Neurological Disorders and Stroke
NIH RePORTER: K23NS135108
Contact: gholipourlab@ucsd.edu