Graves Lab Publications and Media Coverage

Banwell, B., Bennett, J. L., Marignier, R., Kim, H. J., Brilot, F., Flanagan, E. P., ... & Palace, J. (2023). Diagnosis of myelin oligodendrocyte glycoprotein antibody-associated disease: International MOGAD Panel proposed criteria. The Lancet Neurology, 22(3), 268-282.

Graves, J. S., Oertel, F. C., Van der Walt, A., Collorone, S., Sotirchos, E. S., Pihl-Jensen, G., ... & IMSVISUAL. (2021). Leveraging visual outcome measures to advance therapy development in neuroimmunologic disorders. Neurology: Neuroimmunology & Neuroinflammation, 9(2), e1126.

Gaudioso, C. M., Mar, S., Casper, T. C., Codden, R., Nguyen, A., Aaen, G., ... & United States Network of Pediatric Multiple Sclerosis Centers. (2023). MOG and AQP4 antibodies among children with multiple sclerosis and controls. Annals of Neurology, 93(2), 271-284.

Hurtubise, B., Frohman, E. M., Galetta, S., Balcer, L. J., Frohman, T. C., Lisak, R. P., ... & Amezcua, L. (2022). MOG Antibody–Associated Disease and Thymic Hyperplasia: From the National Multiple Sclerosis Society Case Conference Proceedings. Neurology: Neuroimmunology & Neuroinflammation, 10(2), e200077.

Solomon, A. J., Arrambide, G., Brownlee, W. J., Flanagan, E. P., Amato, M. P., Amezcua, L., ... & Cohen, J. A. (2023). Differential diagnosis of suspected multiple sclerosis: an updated consensus approach. The Lancet Neurology, 22(8), 750-768.

Roy, S., Barreras, P., Pardo, C. A., Graves, J. S., Zamvil, S. S., & Newsome, S. D. (2023). Relapsing Encephalomyelitis After COVID-19 Infection and Vaccination: From the National MS Society Case Conference Proceedings. Neurology: Neuroimmunology & Neuroinflammation, 10(3), e200112.

Yeh, E. A., Graves, J. S., Benson, L. A., Wassmer, E., & Waldman, A. (2016). Pediatric optic neuritis. Neurology, 87(9_Supplement_2), S53-S58.

Yang, J. H., Miner, A. E., Fair, A., Kinkel, R., & Graves, J. S. (2024). Senescence marker p16INK4a expression in patients with multiple sclerosis. Multiple Sclerosis and Related Disorders, 105498. 

Goyne, C. E., Fair, A. E., Sumowski, P. E., & Graves, J. S. (2024). The Impact of Aging on Multiple Sclerosis. Current Neurology and Neuroscience Reports, 1-11.

Krysko, K, Henry, RG, Cree, BAC, Lin, Jue, UCSF-EPIC Team, Caillier, S, Santaniello, A, Zhao, C, Gomez, R, Bevan, C, Smith, D, Stern, W, Lirkish, G, Hauser, SL, Oksenberg, JR, Graves, JS. Telomere length is associated with disability progression in multiple sclerosis. Ann Neurol. 2019 Sep 4. doi: 10.1002/ana.25592. [Epub ahead of print].

Graves, JS, Henry, RG, Cree, BA, et al. Ovarian Aging is associated with gray matter volume and disability in women with MS. Neurology. 2018 Jan 16; 90(3):e254-260.

Minner, A, et al. The NHANES Biological Age Index demonstrates accelerated aging in MS patients. (https://doi.org/10.1016/j.msard.2023.104859)

Montalban X, Graves J, Midaglia L, Mulero P, Julian L, Baker M, Schadrack J, Gossens C, Ganzetti M, Scotland A, Lipsmeier F, van Beek J, Bernasconi C, Belachew S, Lindemann M, Hauser SL. A smartphone sensor-based digital outcome assessment of multiple sclerosis. Mult Scler. 2022 Apr;28(4):654-664. doi: 10.1177/13524585211028561. Epub 2021 Jul 14. PMID: 34259588.

Cheng WY, Bourke AK, Lipsmeier F, Bernasconi C, Belachew S, Gossens C, Graves JS, Montalban X, Lindemann M. U-turn speed is a valid and reliable smartphone-based measure of multiple sclerosis-related gait and balance impairment. Gait Posture. 2021 Feb;84:120-126. doi: 10.1016/j.gaitpost.2020.11.025. Epub 2020 Nov 25. PMID: 33310432.

Midaglia L, Mulero P, Montalban X, Graves J, Hauser SL, Julian L, Baker M, Schadrack J, Gossens C, Scotland A, Lipsmeier F, van Beek J, Bernasconi C, Belachew S, Lindemann M. Adherence and Satisfaction of Smartphone- and Smartwatch-Based Remote Active Testing and Passive Monitoring in People With Multiple Sclerosis: Nonrandomized Interventional Feasibility Study. J Med Internet Res. 2019 Aug 30;21(8):e14863. PMID: 31471961.

Krysko, KM, Akhbardeh, A, Arjona, J, Nourbakhsh, B, Waubant, E, Gourraud, PA, Graves, J. Novel multi-sensor algorithm captures subtle progression over one year in multiple sclerosis. ECTRIMS, Berlin, October 12, 2018; 232030. http://www.professionalabstracts.com/ectrims2018/iplanner/#/presentation/349.

Graves, JS, Arjona, J, Gourraud, PA. Wearable electromyogram device associated with disability outcomes in adults with multiple sclerosis. American Academy of Neurology, Boston, MA, 2017. Neurology. April 18, 2017; 88 (16 Supplement)

Block VJ, Bove R, Zhao C, Garcha P, Graves J, Romeo AR, Green AJ, Allen DD, Hollenbach JA, Olgin JE, Marcus GM, Pletcher MJ, Cree BAC, Gelfand JM. Association of Continuous Assessment of Step Count by Remote Monitoring With Disability Progression Among Adults With Multiple Sclerosis. JAMA Netw Open. 2019 Mar 1;2(3):e190570. PMID: 30874777.

Akhmadeev, K, Houssein, A, Moussaoui, S, Hogestol, E, Tutturen, I, Harbo, H, Bos-Haugen, S, Graves, J, Laplaud, DA, Gourraud, PA. SVM-Based Tool to Detect Patients with Multiple Sclerosis using Commercial EMG Sensor. 2018 IEEE 10th Sensor Array and Multichannel Signal Processing (2018) 376-379.

Yousef A, Jonzzon S, Suleiman L, Arjona J, Graves JS. Biosensing in multiple sclerosis. Expert Rev Med Devices. 2017 Nov;14(11):901-912.

Damotte V, Lizée A, Tremblay M, Agrawal A, Khankhanian P, Santaniello A, Gomez R, Lincoln R, Tang W, Chen T, Lee N, Villoslada P, Hollenbach JA, Bevan CD, Graves J, Bove R, Goodin DS, Green AJ, Baranzini SE, Cree BA, Henry RG, Hauser SL, Gelfand JM, Gourraud PA. Harnessing electronic medical records to advance research on multiple sclerosis. Mult Scler. 2019 Mar;25(3):408-418. doi: 10.1177/1352458517747407. Epub 2018 Jan 9.

Yeh EA, Grover SA, Powell VE, Alper G, Banwell BL, Edwards K, Gorman M, Graves J, Lotze TE, Mah JK, Mednick L, Ness J, Obadia M, Slater R, Waldman A, Waubant E, Schwartz CE; Pediatric MS Adherence Study Group. Impact of an electronic monitoring device and behavioral feedback on adherence to multiple sclerosis therapies in youth: results of a randomized trial. Qual Life Res. 2017 Sep;26(9):2333-2349.

Block VJ, Lizée A, Crabtree-Hartman E, Bevan CJ, Graves JS, et al. Continuous daily assessment of multiple sclerosis disability using remote step count monitoring. J Neurol. 2017 Feb;264(2):316-326.

Yeh EA, Grover SA, Powell VE, Alper G, Banwell BL, Edwards K, Gorman M, Graves J, Lotze TE, Mah JK, Mednick L, Ness J, Obadia M, Slater R, Waldman A, Waubant E, Schwartz CE; Pediatric MS Adherence Study Group. Impact of an electronic monitoring device and behavioral feedback on adherence to multiple sclerosis therapies in youth: results of a randomized trial. Qual Life Res. 2017 Apr 9. doi: 10.1007/s11136-017-1571-z. [Epub ahead of print].

Fitzgerald KC, Smith MD, Kim S, Sotirchos ES, Kornberg MD, Douglas M, Nourbakhsh B, Graves J, Rattan R, Poisson L, Cerghet M, Mowry EM, Waubant E, Giri S, Calabresi PA, Bhargava P. Multi-omic evaluation of metabolic alterations in multiple sclerosis identifies shifts in aromatic amino acid metabolism. Cell Rep Med. 2021 Oct 19;2(10):100424. doi: 10.1016/j.xcrm.2021.100424. PMID: 34755135; PMCID: PMC8561319.

Graves JS, Barcellos LF, Krupp L, Belman A, Shao X, Quach H, Hart J, Chitnis T, Weinstock-Guttman B, Aaen G, Benson L, Gorman M, Greenberg B, Lotze T, Soe M, Ness J, Rodriguez M, Rose J, Schreiner T, Tillema JM, Waldman A, Casper TC, Waubant E. Vitamin D genes influence MS relapses in children. Mult Scler. 2019 May 13:1352458519845842. doi: 10.1177/1352458519845842. [Epub ahead of print]. PMID: 31081484.

Rhead B, Shao X, Graves JS, Chitnis T, Waldman AT, Lotze T, Schreiner T, Belman A, Krupp L, Greenberg BM, Weinstock-Guttman B, Aaen G, Tillema JM, Rodriguez M, Hart J, Caillier S, Ness J, Harris Y, Rubin J, Candee MS, Gorman M, Benson L, Mar S, Kahn I, Rose J, Casper TC, Quach H, Quach D, Schaefer C, Waubant E, Barcellos LF; US Network of Pediatric MS Centers. miRNA contributions to pediatric-onset multiple sclerosis inferred from GWAS. Ann Clin Transl Neurol. 2019 May 15;6(6):1053-1061. doi: 10.1002/acn3.786. eCollection 2019 Jun. PMID 31211169.

Graves, JS, Barcellos, LF, Simpson, S, Belman, A, Lin, R, Taylor, B, Ponsonby, AL, Dwyer, T, Krupp, L, Waubant, E, Van der Mei, IAF. The multiple sclerosis risk allele within the AHI1 gene is associated with relapses in children and adults. Mult Scler Relat Disord. 2018 Jan;19:161-165.

Zhou Y, Graves JS, Simpson S Jr, Charlesworth JC, Mei IV, Waubant E, Barcellos LF, Belman A, Krupp L, Lucas R, Ponsonby AL, Taylor BV; Ausimmmune/AusLong investigators group. Genetic variation in the gene LRP2 increases relapse risk in multiple sclerosis. J Neurol Neurosurg Psychiatry. 2017 Oct;88(10):864-868.

Graves JS, Barcellos LF, Shao X, Noble J, Mowry EM, Quach H, Belman A, Casper TC, Krupp LB, Waubant E. Genetic predictors of relapse rate in pediatric MS. Mult Scler. 2016 Jan 14. PMID: 26769066.

Chi C, Shao X, Rhead B, Gonzales E, Smith JB, Xiang AH, Graves J, Waldman A, Lotze T, Schreiner T, Weinstock-Guttman B, Aaen G, Tillema JM, Ness J, Candee M, Krupp L, Gorman M, Benson L, Chitnis T, Mar S, Belman A, Casper TC, Rose J, Moodley M, Rensel M, Rodriguez M, Greenberg B, Kahn L, Rubin J, Schaefer C, Waubant E, Langer-Gould A, Barcellos LF. Admixture mapping reveals evidence ofdifferential multiple sclerosis risk by genetic ancestry. PLoS Genet. 2019 Jan 17;15(1):e1007808.

Graves, JS, Barcellos, LF, Simpson, S, Belman, A, Lin, R, Taylor, B, Ponsonby, AL, Dwyer, T, Krupp, L, Waubant, E, Van der Mei, IAF. The multiple sclerosis risk allele within the AHI1 gene is associated with relapses in children and adults. Mult Scler Relat Disord. 2018 Jan;19:161-165.

Gianfrancesco MA, Stridh P, Shao X, Rhead B, Graves JS, Chitnis T, Waldman A, Lotze T, Schreiner T, Belman A, Greenberg B, Weinstock-Guttman B, Aaen G, Tillema JM, Hart J, Caillier S, Ness J, Harris Y, Rubin J, Candee M, Krupp L, Gorman M, Benson L, Rodriguez M, Mar S, Kahn I, Rose J, Roalstad S, Casper TC, Shen L, Quach H, Quach D, Hillert J, Hedstrom A, Olsson T, Kockum I, Alfredsson L, Schaefer C, Barcellos LF, Waubant E; Network of Pediatric Multiple Sclerosis Centers. Genetic risk factors for pediatric-onset multiplesclerosis. Mult Scler. 2017 Oct 1 [Epub ahead of print].

Zhou Y, Graves JS, Simpson S Jr, Charlesworth JC, Mei IV, Waubant E, Barcellos LF, Belman A, Krupp L, Lucas R, Ponsonby AL, Taylor BV; Ausimmmune/AusLong investigators group. Genetic variation in the gene LRP2 increases relapse risk in multiple sclerosis. J Neurol Neurosurg Psychiatry. 2017 Oct;88(10):864-868.

Graves JS, Barcellos LF, Shao X, Noble J, Mowry EM, Quach H, Belman A, Casper TC, Krupp LB, Waubant E. Genetic predictors of relapse rate in pediatric MS. Mult Scler. 2016 Jan 14. PMID: 26769066

Horton MK, McCauley K, Fadrosh D, Fujimura K, Graves J, Ness J, Wheeler Y, Gorman MP, Benson LA, Weinstock-Guttman B, Waldman A, Rodriguez M, Tillema JM, Krupp L, Belman A, Mar S, Rensel M, Chitnis T, Casper TC, Rose J, Hart J, Shao X, Tremlett H, Lynch SV, Barcellos LF, Waubant E; U.S. Network of Pediatric MS Centers. Gut microbiome is associated with multiple sclerosis activity in children. Ann Clin Transl Neurol. 2021 Sep;8(9):1867-1883. doi: 10.1002/acn3.51441. Epub 2021 Aug 19. PMID: 34409759; PMCID: PMC8419410.

Pröbstel AK, Zhou X, Baumann R, Wischnewski S, Kutza M, Rojas OL, Sellrie K, Bischof A, Kim K, Ramesh A, Dandekar R, Greenfield AL, Schubert RD, Bisanz JE, Vistnes S, Khaleghi K, Landefeld J, Kirkish G, Liesche-Starnecker F, Ramaglia V, Singh S, Tran EB, Barba P, Zorn K, Oechtering J, Forsberg K, Shiow LR, Henry RG, Graves J, Cree BAC, Hauser SL, Kuhle J, Gelfand JM, Andersen PM, Schlegel J, Turnbaugh PJ, Seeberger PH, Gommerman JL, Wilson MR, Schirmer L, Baranzini SE. Gut microbiota-specific IgA⁺ B cells traffic to the CNS in active multiple sclerosis. Sci Immunol. 2020 Nov 20;5(53):eabc7191. doi: 10.1126/sciimmunol.abc7191. PMID: 33219152

The iMSMS Consortium. Household paired design reduces variance and increases power in multi-city gut microbiome study in multiple sclerosis. Mult Scler. 2020 Jun 26:1352458520924594. doi: 10.1177/1352458520924594. Epub ahead of print. PMID: 33115343.

Cekanaviciute E, Pröbstel AK, Thomann A, Runia TF, Casaccia P, Katz Sand I, Crabtree E, Singh S, Morrissey J, Barba P, Gomez R, Knight R, Mazmanian S, Graves J, Cree BAC, Zamvil SS, Baranzini SE. Multiple Sclerosis-Associated Changes in the Composition and Immune Functions of Spore-Forming Bacteria. mSystems. 2018 Nov 6;3(6). pii: e00083-18.

Tremlett, H, Fadrosh, DW, Faruqi, AA, Hart, J, Roalstad, S, Graves, J, Spencer, CM, Lynch, SV, Zamvil, S, Waubant, E, on behalf of the US Network of Pediatric MS Centers. Associations between the gut microbiota and host immune markers in pediatric multiple sclerosis and controls. BMC Neurology. 2016, 16:182.

Tremlett, H, Fadrosh, D, Faruqi, A, Hart, J, Graves, JS, Lynch, S, Waubant, E, on behalf of the US Network of Pediatric MS Centers. Gut microbiome in early pediatric multiple sclerosis: a case-control study. Eur J Neurol. 2016 Aug;23(8):1308-21.

Tremlett H, Fadrosh DW, Faruqi AA, Hart J, Roalstad S, Graves J, Lynch S, Waubant E, on behalf of the US Network of Pediatric MS Centers. Gut microbiota composition and relapse risk in pediatric MS: a pilot study. Journal of the Neurological Sciences 2016 Apr 15;363:153-7.

Bischof A, Papinutto N, Keshavan A, Rajesh A, Kirkish G, Zhang X, Mallott JM, Asteggiano C, Sacco S, Gundel TJ, Zhao C, Stern WA, Caverzasi E, Zhou Y, Gomez R, Ragan NR, Santaniello A, Zhu AH, Juwono J, Bevan CJ, Bove RM, Crabtree E, Gelfand JM, Goodin DS, Graves JS, Green AJ, Oksenberg JR, Waubant E, Wilson MR, Zamvil SS; University of California, San Francisco MS-EPIC Team, Cree BAC, Hauser SL, Henry RG. Spinal Cord Atrophy Predicts Progressive Disease in Relapsing Multiple Sclerosis. Ann Neurol. 2022 Feb;91(2):268-281. doi: 10.1002/ana.26281. Epub 2022 Jan 4. PMID: 34878197; PMCID: PMC8916838.

Krysko KM, Akhbardeh A, Arjona J, Nourbakhsh B, Waubant E, Antoine Gourraud P, Graves JS. Biosensor vital sign detects multiple sclerosis progression. Ann Clin Transl Neurol. 2021 Jan;8(1):4-14. doi: 10.1002/acn3.51187. Epub 2020 Nov 19. PMID: 33211403; PMCID: PMC7818086.

Raynowska J, Graves JS. Dermatographism associated with ocrelizumab. Mult Scler Relat Disord. 2020 Nov;46:102505. doi: 10.1016/j.msard.2020.102505. Epub 2020 Sep 13. PMID: 32979732.

UCSF MS-EPIC Team, Cree BAC, Hollenbach JA, Bove R, Kirk. ish G, Sacco S, Caverzasi E, Bischof A, Gundel T, Zhu AH, Papinutto N, Stern WA, Bevan C, Romeo A, Goodin DS, Gelfand JM, Graves J, Green AJ, Wilson MR, Zamvil SS, Zhao C, Gomez R, Ragan NR, Rush GQ, Barba P, Santaniello A, Baranzini SE, Oksenberg JR, Henry RG, Hauser SL. Silent Progression in DiseaseActivity-Free Relapsing Multiple Sclerosis. Ann Neurol. 2019 Mar 9. doi: 10.1002/ana.25463. [Epub ahead of print].

Hatcher, SE, Waubant, E, Nourbakhsh, B, Crabtree-Hartman, E, Graves, JS. Rebound syndrome in patients with multiple sclerosis after cessation of fingolimod treatment. JAMA Neurol. 2016 Jul 1;73(7):790-4

Hatcher SE, Waubant E, Graves JS. Rebound Syndrome in Multiple Sclerosis After Fingolimod Cessation-Reply. JAMA Neurol. 2016 Nov 1; 73(11):1376. PMID: 27669526.

Cree, B, Gourraud, PA, Oksenberg, J, Bevan C, Crabtree-Hartman, L, Gelfand, J, Goodin, D, Graves, J, et al. Long-term evolution of multiple sclerosis disability in the treatment era. Ann Neurol. 2016 Jul 27. PMID: 27464262. PMCID: PMC5105678.

Chohan H, Greenfield AL, Yadav V, Graves J. Use of Cannabinoids for Spasticity and Pain Management in MS. Curr Treat Options Neurol. 2016 Jan; 18(1):1. PMID: 26705757

Weinfurtner K, Graves J, Ness J, Krupp L, Milazzo M, Waubant E. Prolonged Remission in Neuromyelitis Optica Following Cessation of Rituximab Treatment. J Child Neurol. 2015 Sep; 30(10):1366-70. PMID: 25387545

Schlaeger R, Papinutto N, Zhu AH, Lobach IV, Bevan CJ, Bucci M, Castellano A, Gelfand JM, Graves JS, Green AJ, Jordan KM, Keshavan A, Panara V, Stern WA, von Büdingen HC, Waubant E, Goodin DS, Cree BA, Hauser SL, Henry RG. Schlaeger R, Papinutto N, Zhu AH, Lobach IV, Bevan CJ, Bucci M, Castellano A, Gelfand JM, Graves JS, Green AJ, Jordan KM, Keshavan A, Panara V, Stern WA, von Büdingen HC, Waubant E, Goodin DS, Cree BA, Hauser SL, Henry RG. Association Between Thoracic Spinal Cord Gray Matter Atrophy and Disability in Multiple Sclerosis. JAMA Neurol. 2015 Aug 1; 72(8):897-904. PMID: 26053119

Beres SJ, Graves J, Waubant E. Rituximab use in pediatric central demyelinating disease. Pediatr Neurol. 2014 Jul; 51(1):114-8. PMID: 24768216

Graves J, Galetta SL, Palmer J, Margolin DH, Rizzo M, Bilbruck J, Balcer LJ. Alemtuzumab improves contrast sensitivity in patients with relapsing-remitting multiple sclerosis. Mult Scler. 2013 Sep; 19(10):1302-9. PMID: 23459567

Turkeltaub PE, Graves J. Teaching neuroimages: hemorrhage associated with reversible posterior leukoencephalopathy syndrome. Neurology. 2009 Aug 11; 73(6):e30. PMID: 19667315

Graves JS, Oertel FC, Van der Walt A, Collorone S, Sotirchos ES, Pihl-Jensen G, Albrecht P, Yeh EA, Saidha S, Frederiksen J, Newsome SD, Paul F; IMSVISUAL. Leveraging Visual Outcome Measures to Advance Therapy Development in Neuroimmunologic Disorders. Neurol Neuroimmunol Neuroinflamm. 2021 Dec 26;9(2):e1126. doi: 10.1212/NXI.0000000000001126. PMID: 34955459; PMCID: PMC8711076.

Rempe T, Dastgheyb N, Miner A, Palomino M, Kinkel R, Liston D, Graves JS. Quantification of smooth pursuit dysfunction in multiple sclerosis. Mult Scler Relat Disord. 2021 Sep;54:103073. doi: 10.1016/j.msard.2021.103073. Epub 2021 Jun 5. PMID: 34214878

Graves, JS, Chohan, H, Cedars, B, Arnow, S, Yiu, H., Waubant, E, Green, A. Sex differences and subclinical retinal injury in pediatric-onset MS. Mult Scler. 2017 Mar; 23 (3):447-455.

Yousef A, Devereux M, Gourraud PA, Jonzzon S, Suleiman L, Waubant E, Green A, Graves JS. Subclinical Saccadic Eye Movement Dysfunction in Pediatric Multiple Sclerosis. J Child Neurol. 2019 Jan;34(1):38-43.

Graves, JS, Chohan, H, Cedars, B, Arnow, S, Yiu, H., Waubant, E, Green, A. Sex differences and subclinical retinal injury in pediatric-onset MS. Mult Scler. 2017 Mar; 23 (3):447-455.

Petzold A, Balcer LJ, Calabresi PA, Costello F, Frohman TC, Frohman EM, Martinez- Lapiscina EH, Green AJ, Kardon R, Outteryck O, Paul F, Schippling S, Vermersch P, Villoslada P, Balk LJ; ERN-EYE IMSVISUAL (including Graves, J). Retinal layer segmentationin multiple sclerosis: a systematic review and meta-analysis. Lancet Neurol. 2017 Oct;16(10):797-812.

Chitnis T, Ness J, Krupp L, Waubant E, Hunt T, Olsen CS, Rodriguez M, Lotze T, Gorman M, Benson L, Belman A, Weinstock-Guttman B, Aaen G, Graves J, Patterson M, Rose JW, Casper TC. Clinical features of neuromyelitis optica in children: US Network of Pediatric MS Centers report. Neurology. 2016 Jan 19; 86(3):245-52. PMID: 26683648. PMCID: PMC4733158

Maghzi AH, Graves J, Revirajan N, Spain R, Liu S, McCulloch CE, Pelletier D, Green AJ, Waubant E. Retinal axonalloss in very early stages of multiplesclerosis. Eur J Neurol. 2015 Jul; 22(7):1138-41. PMID: 25929276

Kraus V, Soares BP, Hess CP, Waubant E. Longitudinally extensive optic neuritis in pediatric patients. J Child Neurol. 2015 Jan; 30(1):120-3. PMID: 24563470

Graves J, Grandhe S, Weinfurtner K, Krupp L, Belman A, Chitnis T, Ness J, Weinstock- Guttman B, Gorman M, Patterson M, Rodriguez M, Lotze T, Aaen G, Mowry EM, Rose JW, Simmons T, Casper TC, James J, Waubant E. Protective environmental factors for neuromyelitis optica. Neurology. 2014 Nov 18; 83(21):1923-9. PMID: 25339213. PMCID: PMC4248458

Galetta KM, Graves J, Talman LS, Lile DJ, Frohman EM, Calabresi PA, Galetta SL, Balcer LJ. Visual pathway axonal loss in benign multiple sclerosis: a longitudinal study. J Neuroophthalmol. 2012 Jun; 32(2):116-23. PMID: 22269944. PMCID: PMC3427935

Gelfand JM, Nolan R, Schwartz DM, Graves J, Green AJ. Microcystic macular oedema in multiple sclerosis is associated with disease severity. Brain. 2012 Jun; 135(Pt 6):1786-93. PMID: 22539259. PMCID: PMC3359753.

Sebastian P, Cherbuin N, Barcellos LF, Roalstad S, Casper C, Hart J, Aaen GS, Krupp L, Benson L, Gorman M, Candee M, Chitnis T, Goyal M, Greenberg B, Mar S, Rodriguez M, Rubin J, Schreiner T, Waldman A, Weinstock-Guttman B, Graves J, Waubant E, Lucas R; US Network of Pediatric Multiple Sclerosis Centers. Association Between Time Spent Outdoors and Risk of Multiple Sclerosis. Neurology. 2022 Jan 18;98(3):e267-e278. doi

Ziaei A, Lavery AM, Shao XM, Adams C, Casper TC, Rose J, Candee M, Weinstock-Guttman B, Aaen G, Harris Y, Graves J, Benson L, Gorman M, Rensel M, Mar S, Lotze T, Greenberg B, Chitnis T, Hart J, Waldman AT, Barcellos LF, Waubant E. Gene-environment interactions increase the risk of pediatric-onset multiple sclerosis associated with ozone pollution. Mult Scler. 2022 Jan 8:13524585211069926. doi: 10.1177/13524585211069926. Epub ahead of print. PMID: 35000467.

Greenberg BM, Casper TC, Mar SS, Ness JM, Plumb P, Liang S, Goyal M, Weinstock-Guttman B, Rodriguez M, Aaen GS, Belman A, Barcellos LF, Rose JW, Gorman MP, Benson LA, Candee M, Chitnis T, Harris YC, Kahn IL, Roalstad S, Hart J, Lotze TE, Rensel M, Rubin JP, Schreiner TL, Tillema JM, Waldman AT, Krupp L, Graves J, Drake K, Waubant E. Familial History of Autoimmune Disorders Among Patients With Pediatric Multiple Sclerosis. Neurol Neuroimmunol Neuroinflamm. 2021 Aug 5;8(5):e1049. doi: 10.1212/NXI.0000000000001049. PMID: 34353894; PMCID: PMC8362349.

Krysko KM, Graves JS, Rensel M, Weinstock-Guttman B, Rutatangwa A, Aaen G, Belman A, Benson L, Chitnis T, Gorman M, Goyal MS, Harris Y, Krupp L, Lotze T, Mar S, Moodley M, Ness J, Rodriguez M, Rose J, Schreiner T, Tillema JM, Waltz M, Casper TC, Waubant E; US Network of Pediatric MS Centers. Real-World Effectiveness of Initial Disease-Modifying Therapies in Pediatric Multiple Sclerosis. Ann Neurol. 2020 Jul;88(1):42-55. doi: 10.1002/ana.25737. Epub 2020 May 14. PMID: 32267005.

Graves, JS, Chitnis, T, Weinstock-Gutman, B, et al. Maternal and Perinatal Exposures Are Associated with Risk for Pediatric-Onset Multiple Sclerosis. Pediatrics. 2017 Apr; 139(4).

Manguinao M, Krysko KM, Maddike S, Rutatangwa A, Francisco C, Hart J, Chong J, Graves JS, Waubant E. A retrospective cohort study of plasma exchange in central nervous system demyelinating events in children. Mult Scler Relat Disord. 2019 Jul 8;35:50-54. PMID 31319355.

Rhead B, Shao X, Graves JS, Chitnis T, Waldman AT, Lotze T, Schreiner T, Belman A, Krupp L, Greenberg BM, Weinstock-Guttman B, Aaen G, Tillema JM, Rodriguez M, Hart J, Caillier S, Ness J, Harris Y, Rubin J, Candee MS, Gorman M, Benson L, Mar S, Kahn I, Rose J, Casper TC, Quach H, Quach D, Schaefer C, Waubant E, Barcellos LF; US Network of Pediatric MS Centers. miRNA contributions to pediatric-onset multiple sclerosisinferred from GWAS. Ann Clin Transl Neurol. 2019 May 15;6(6):1053-1061. doi: 10.1002/acn3.786. eCollection 2019 Jun. PMID 31211169

Graves JS, Barcellos LF, Krupp L, Belman A, Shao X, Quach H, Hart J, Chitnis T, Weinstock-Guttman B, Aaen G, Benson L, Gorman M, Greenberg B, Lotze T, Soe M, Ness J, Rodriguez M, Rose J, Schreiner T, Tillema JM, Waldman A, Casper TC, Waubant E. Vitamin D genes influence MS relapses inchildren. Mult Scler. 2019 May 13:1352458519845842. doi: 10.1177/1352458519845842. [Epub ahead of print]. PMID: 31081484

Young B, Waubant E, Lulu S, Graves J. Puberty onset and pediatric multiple sclerosis activity in boys. Mult Scler Relat Disord. 2019 Jan;27:184-187.

Aaen G, Waltz M, Vargas W, Makhani N, Ness J, Harris Y, Casper TC, Benson L, Candee M, Chitnis T, Gorman M, Graves J, Greenberg B, Lotze T, Mar S, Tillema JM, Rensel M, Rodriguez M, Rose J, Rubin J, Schreiner T, Waldman A, Weinstock-Guttman B, Belman A, Waubant E, Krupp L. Acquisition of EarlyDevelopmental Milestones and Need for Special Education Services in PediatricMultiple Sclerosis. J Child Neurol. 2018 Dec 17:883073818815041. doi: 10.1177/0883073818815041. [Epub ahead of print].

Krysko KM, Graves J, Rensel M, Weinstock-Guttman B, Aaen G, Benson L, Chitnis T, Gorman M, Goyal M, Krupp L, Lotze T, Mar S, Rodriguez M, Rose J, Waltz M, Charles Casper T, Waubant E; US Network of Pediatric MS Centers. Use of newer disease-modifying therapies in pediatric multiple sclerosis in the US. Neurology. 2018 Nov 6;91(19):e1778-e1787.

Mar S, Liang S, Waltz M, Casper TC, Goyal M, Greenberg B, Weinstock-Guttman B, Rodriguez M, Aaen G, Belman A, Barcellos LF, Rose J, Gorman M, Benson L, Candee M, Chitnis T, Harris Y, Kahn I, Roalsted S, Hart J, Lotze T, Moodley M, Ness J, Rensel M, Rubin J, Schreiner T, Tillema JM, Waldman A, Krupp L, Graves JS, Waubant E. Several household chemical exposures are associated with pediatric-onset multiple sclerosis. Ann Clin Transl Neurol. 2018 Oct 9;5(12):1513-1521.

Bartolini L, Piras E, Sullivan K, Gillen S, Bumbut A, Lin CM, Leibovitch EC, Graves JS, Waubant EL, Chamberlain JM, Gaillard WD, Jacobson S. Detection of HHV-6 and EBV and Cytokine Levels in Saliva From Children With Seizures: Results of a Multi-Center Cross-Sectional Study. Front Neurol. 2018 Oct 5;9:834.

Lavery AM, Waubant E, Casper TC, Roalstad S, Candee M, Rose J, Belman A, Weinstock-Guttman B, Aaen G, Tillema JM, Rodriguez M, Ness J, Harris Y, Graves J, Krupp L, Charvet L, Benson L, Gorman M, Moodley M, Rensel M, Goyal M, Mar S, Chitnis T, Schreiner T, Lotze T, Greenberg B, Kahn I, Rubin J, Waldman AT. Urban air quality and associations with pediatric multiple sclerosis. Ann Clin Transl Neurol. 2018 Sep 27;5(10):1146-1153.

Nourbakhsh B, Bhargava P, Tremlett H, Hart J, Graves J, Waubant E. Altered tryptophan metabolism is associated with pediatric multiple sclerosis risk and course. Ann Clin Transl Neurol. 2018 Sep 27;5(10):1211-1221.

Nourbakhsh B, Rutatangwa A, Waltz M, Rensel M, Moodley M, Graves J, Casper TC, Waldman A, Belman A, Greenberg B, Goyal M, Harris Y, Kahn I, Lotze T, Mar S, Schreiner T, Aaen G, Hart J, Ness J, Rubin J, Tillema JM, Krupp L, Gorman M, Benson L, Rodriguez M, Chitnis T, Rose J, Candee M, Weinstock-Guttman B, Shao X, Barcellos L, James J, Waubant E; US Network of Pediatric MS Centers. Heterogeneity in association of remote herpesvirus infections and pediatric MS. Ann Clin Transl Neurol. 2018 Sep 17;5(10):1222-1228.

Suleiman L, Waubant E, Aaen G, Belman A, Benson L, Candee M, Chitnis T, Gorman M, Goyal M, Greenberg B, Harris Y, Hart J, Kahn I, Krupp L, Lotze T, Mar S, Moodley M, Ness J, Nourbakhsh B, Rensel M, Rodriguez M, Rose J, Rubin J, Schreiner T, Tillema JM, Waldman A, Weinstock-Guttman B, Casper TC, Waltz M, Graves JS. Early infectious exposures are not associated withincreased risk of pediatric-onset multiple sclerosis. Mult Scler Relat Disord. 2018 Mar 26;22:103-107.

Leibovitch EC, Lin CM, Billioux BJ, Graves J, Waubant E, Jacobson S. Prevalence of salivary human herpesviruses in pediatric multiple sclerosis cases and controls. Mult Scler Relat Disord. 2018 May;22:103-107.

Azary S, Schreiner T, Graves J, Waldman A, Belman A, Guttman BW, Aaen G, Tillema JM, Mar S, Hart J, Ness J, Harris Y, Krupp L, Gorman M, Benson L, Rodriguez M, Chitnis T, Rose J, Barcellos LF, Lotze T, Carmichael SL, Roalstad S, Casper CT, Waubant E. Contribution of dietary intake to relapse rate in early paediatric multiple sclerosis. J Neurol Neurosurg Psychiatry. 2018 Jan;89(1):28-33.

Lavery AM, Waldman AT, Charles Casper T, Roalstad S, Candee M, Rose J, Belman A, Weinstock-Guttman B, Aaen G, Tillema JM, Rodriguez M, Ness J, Harris Y, Graves J, Krupp L, Benson L, Gorman M, Moodley M, Rensel M, Goyal M, Mar S, Chitnis T, Schreiner T, Lotze T, Greenberg B, Kahn I, Rubin J, Waubant E; U.S. Network of Pediatric MS Centers. Examining the contributions of environmental quality to pediatric multiple sclerosis. Mult Scler Relat Disord. 2017 Nov;18:164-169.

Graves, JS, Chitnis, T, Weinstock-Guttman, B, et al. Maternal and perinatal exposures are associated with risk for pediatric-onset multiple sclerosis. Pediatrics. 2017 Apr;139(4).

Gianfrancesco MA, Stridh P, Rhead B, Shao X, Xu E, Graves JS, et al. Evidence for a causal relationship between low vitamin D, high BMI, and pediatric-onset MS. Neurology. 2017 Mar 29. PMID: 28356466.

Pakpoor, J., Seminatore, B, Graves, J, Schreiner, T, Waldman A, Lotze, T, et al on behalf of the US Network of Pediatric MS Centers. Dietary factors and pediatric multiple sclerosis susceptibility: A case-control study. Mult Scler. 2017 Jun 1. [Epub ahead of print] PMID: 28608728

Chitnis, T, Graves, J, Weinstock-Guttman, B, et al. Distinct effects of obesity and puberty on risk and age at onset of pediatric MS. Annals of Clinical and Translational Neurology 2016 Nov 4;3(12):897-907.

Hanumanthe SB, Francisco C, Hart J, Graves J, Waubant E. Biopsy-Supported Tumefactive Demyelination of the Central Nervous System in Children. J Child Neurol. 2016 Dec; 31(14):1528-1533. PMID: 27572815

Nourbakhsh B, Graves J, Casper TC, Lulu S, Waldman A, Belman A, Greenberg B, Weinstock-Guttman B, Aaen G, Tillema JM, Hart J, Ness J, Rubin J, Krupp L, Gorman M, Benson L, Rodriguez M, Chitnis T, Rose J, Barcellos L, Waubant E; Network of Pediatric Multiple Sclerosis Centers. Dietary salt intake and time to relapse in paediatric multiple sclerosis. J Neurol Neurosurg Psychiatry. 2016 Dec;87(12):1350-1353. doi: 10.1136/jnnp- 2016-313410. Epub 2016 Jun 24.

Francisco, C Graves, J, Waubant, E. Clinical trials for pediatric MS should be prioritized to test only one or two of the most promising agents. MSJ epub ahead of print Jul 28 2016.

Bedmar, SV, Waubant, E, Graves, J. Acute demyelination in childhood associated with TNF alpha-inhibitor therapy. Dec 2016. DOI:10.21035/ijcnmh.2016.3(Suppl.1).S09

McDonald J, Graves J, Waldman A, Lotze T, Schreiner T, Belman A, Greenberg B, Weinstock-Guttman B, Aaen G, Tillema JM, Hart J, Lulu S, Ness J, Harris Y, Rubin J, Candee M, Krupp LB, Gorman M, Benson L, Rodriguez M, Chitnis T, Mar S, Barcellos LF, Laraia B, Rose J, Roalstad S, Simmons T, Casper TC, Waubant E. A case-control study of dietary salt intake in pediatric-onset multiple sclerosis. Mult Scler Relat Disord. 2016 Mar; 6:87-92. PMID: 27063630.

Lulu, S, Graves, J, Waubant, E. Menarche increases relapse risk in pediatric multiple sclerosis. Multiple Sclerosis Journal. Mult Scler. 2016 Feb; 22(2):193-200. PMID: 25948626.

Bourne T, Waltz M, Casper TC, Kavak K, Aaen G, Belman A, Benson L, Candee M, Chitnis T, Graves J, Greenberg B, Gorman M, Harris Y, Krupp L, Lotze T, Mar S, Ness J, Olsen C, Roalstad S, Rodriguez M, Rose J, Rubin J, Schreiner T, Tillema JM, Kahn I, Waldman A, Barcellos L, Waubant E, Weinstock-Guttman B; US Network of Pediatric MS Centers. Evaluating the association of allergies with multiple sclerosis susceptibility risk and disease activity in a pediatric population. J Neurol Sci. 2017 Apr 15;375:371-375. Epub 2017 Feb 20.

Graves, JS. Season of birth: is it important for multiple sclerosis risk? JAMA Neurology 2016 Aug 1;73(8):912-3.

Graves, JS and Brashear, A. Editorial: Gender Bias in American Academy of Neurology recognition awards? Neurology July 20, 2018 [epub ahead of print].

Graves, JS. Editorial: Can Visual Testing Be Used to Distinguish Neuromyelitis Optica and Multiple Sclerosis? Ophthalmology March 2019, Volume 126, Issue 3, Pages 454–455.

Yeh, A and Graves JS. Vaccination: Not a trigger for MS. Neurology. July 30 2019; 93:1-2, [Epub ahead of print].

Frohman, T., Graves, J., Balcer, L., Galetta, S. and Frohman, E. The Neuro-Ophthalmology of MS. Continuum (Minneap Minn). 2010 Oct; 16(5 Multiple Sclerosis):122-46. PMID: 22810602

E. Ann Yeh, MD, Jennifer S. Graves, MD, Leslie A. Benson, MD, Evangeline Wassmer, MD, and Amy Waldman, MD. Pediatric Optic Neuritis. Neurology Aug 2016, 87 (9 Supplement 2) S53-S58.

Graves J, Balcer LJ. Eye disorders in patients with multiple sclerosis: natural history and management. Clin Ophthalmol. 2010; 4:1409-22. PMID: 21188152

Graves JS, Galetta SL. Acute visual loss and other neuro-ophthalmologic emergencies: management. Neurol Clin. 2012 Feb; 30(1):75-99, viii. PMID: 22284056

Barcelos, IP, Troxell RM, Graves JS. Mitochondrial Dysfunction and Multiple Sclerosis. Biology (Basel). 2019 May 11; 8(2). PMID 31083577.

Graves JS, Optical Coherence Tomography in Multiple Sclerosis. Seminars in Neurology. In press.

Graves, JS and Montalban, X. Biosensors to monitor MS activity. MSJ Special Edition: ACTRIMS Forum, 2019: Precision medicine Approaches for MS: Scientific Principles to Clinical Application. In press.

Waubant, E, Lucas, R, Mowry, E, Graves, J, Olsson, T, Alfredsson, L, Langer-Gould, A. Environmental and genetic risk factors for MS: an integrated review. Annals of Clinical and Translational Neurology. 2019 Aug 7. doi: 10.1002/acn3.50862. [Epub ahead of print]

Graves J, Waubant EL. Monoclonal antibodies. In: Addressing Unmet Medical Needs in Relapsing-Remitting Multiple Sclerosis. Rudick RA, Bermel RA (Eds). Future Medicine, London, UK, doi:10.2217/EBO.11.122 (2011).

Graves J., Galetta S. Acute visual loss and other neuro-ophthalmological emergencies: Management. Neurologic Clinics: Neurologic Emergencies. Minagar, A., Rabinstein A. (Eds). Elsevier. Volume 30, Issue 1 , Pages 75-99, February 2012.

Tillema, J.M., Graves, J., Benson, L.A., Aaen, G.S., Belman, A., Parrish, J., Weinstock- Guttman, B., Krupp, L., Chitnis, T., Waubant. E. Pediatric Multiple Sclerosis. Primers on Multiple Sclerosis. Editor: Giesser, B. Oxford Press. 2016

Chohan, H. Waubant, E., Graves, J. Steroid-Dependent Recurrent Optic Neuritis in Pediatric Multiple Sclerosis. Pediatric Demyelinating Diseases of the Central Nervous System and Their Mimics. Waubant, E, Lotze, T (Eds). Springer, Cham. Nov 2017.

Yeh, E., A. Graves, J., Boyd, J.  Pediatric MultipleSclerosis: Sourcebook for MS Care Professionals.  International Journal of MS Care.  Supplement.

Timmons GM, Rempe T, Bevins EA, Goodwill V, Miner A, Kavanaugh A, Ritter M, Graves JS. CNS Lymphocytic Vasculitis in a Young Woman With COVID-19 Infection.  Neurol Neuroimmunol Neuroinflamm. 2021 Jul 28;8(5):e1048. doi: 10.1212/NXI.0000000000001048. PMID: 34321332; PMCID: PMC8362344.

Turkeltaub PE, Graves J. Teaching neuroimages: hemorrhage associated with reversible posterior leukoencephalopathy syndrome. Neurology. 2009 Aug 11; 73(6):e30. PMID: 19667315.

Patients May Rebound After Stopping Fingolimod. MedPage Today.

Relapse of MS Can Follow Cessation of FingolimodTreatment. Consultant360.

About 10% Rebound of Multiple Sclerosis WhenImmunomodulator Fingolimod Stopped. Medicalresearch.com. May 2, 2016.

Genetic risk score for low vitamin D may affectMS relapse rate. Clinical Neurology News, MDEdge.

Genetic Risk Score for Vitamin D Predicts MSRelapse. Nancy Melville. MedScape
Study Points Towards Vitamin D for Predicting MSRelapse. MultipleSclerosis.net. December 13, 2016.

Increased Disability, Grey Matter Loss in MS Linked to Anti-Mullerian HormoneLevels. Brandon May. NeurologyAdvisor. January 2018.

Aging Ovaries May Signal Imminent Progression ofMS. Caroline Helwick. Medscape. February 22, 2016.

ACTRIMS: Ovarian decline linked to MSprogression in women. Brian Hoyle. Ob.Gyn. News., MDEdge.

Aging Ovaries may signal imminent MSprogression. MS-UK. February 2016

Small, Wearable Sensor Captures Progression, Limb Dysfunction in Multiple Sclerosis. Laura Stiles. NeurologyAdvisor. February 1, 2018.

Are Some Risk Factors for Multiple SclerosisAvoidable? Kenneth Bender. March 21, 2018. MD Magazine.

Pesticides linked to MS risk. MS-UK. April 18, 2016.

Early life factors influence risk for pediatric-onsetmultiple sclerosis. Stan Grossman. April 16, 2016.

What do we know about pediatric MS? Neurology Reviews. 2016 December;24(12):10.

Telomere Length Tied to MSDisability – Biological as well as chronological aging may contribute todisease progression. Judy George. March 4, 2019. MedPage Today.

Biological aging isassociated with MS disability progression. Jake Remaly, March 1, 2019. MDedge.

MS research: “Our patientscan’t wait” for conventional techniques. Kari Oakes. March 3, 2019. MDedge.
In MS, children aren’t justlittle adults. Randy Dotinga. June 13, 2019. MDedge.