Brewer Lab Publications

1: Spencer BE, Jennings RG, Brewer JB; Alzheimer’s Disease Neuroimaging Initiative. Combined Biomarker Prognosis of Mild Cognitive Impairment: An 11-Year Follow-Up Study in the Alzheimer's Disease Neuroimaging Initiative. J Alzheimers Dis. 2019;68(4):1549-1559. doi: 10.3233/JAD-181243. PubMed PMID: 30958366.

2: Smirnov DS, Galasko D, Hansen LA, Edland SD, Brewer JB, Salmon DP. Trajectories of cognitive decline differ in hippocampal sclerosis and Alzheimer's disease. Neurobiol Aging. 2019 Mar;75:169-177. doi: 10.1016/j.neurobiolaging.2018.11.015. Epub 2018 Nov 22. PubMed PMID: 30579145; PubMed Central PMCID: PMC6492933.

3: Broce IJ, Tan CH, Fan CC, Jansen I, Savage JE, Witoelar A, Wen N, Hess CP, Dillon WP, Glastonbury CM, Glymour M, Yokoyama JS, Elahi FM, Rabinovici GD, Miller BL, Mormino EC, Sperling RA, Bennett DA, McEvoy LK, Brewer JB, Feldman HH, Hyman BT, Pericak-Vance M, Haines JL, Farrer LA, Mayeux R, Schellenberg GD, Yaffe K, Sugrue LP, Dale AM, Posthuma D, Andreassen OA, Karch CM, Desikan RS. Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease. Acta Neuropathol. 2019 Feb;137(2):209-226. doi: 10.1007/s00401-018-1928-6. Epub 2018 Nov 9. PubMed PMID: 30413934; PubMed Central PMCID: PMC6358498.

4: Soria JA, Huisa BN, Edland SD, Litvan I, Peavy GM, Salmon DP, Hansen LA, Galasko DR, Brewer JB, González HM, Rissman RA. Clinical-Neuropathological Correlations of Alzheimer's Disease and Related Dementias in Latino Volunteers. J Alzheimers Dis. 2018;66(4):1539-1548. doi: 10.3233/JAD-180789. PubMed PMID: 30412501.

5: Reas ET, Hagler DJ Jr, White NS, Kuperman JM, Bartsch H, Wierenga CE, Galasko D, Brewer JB, Dale AM, McEvoy LK. Microstructural brain changes track cognitive decline in mild cognitive impairment. Neuroimage Clin. 2018;20:883-891. doi: 10.1016/j.nicl.2018.09.027. Epub 2018 Sep 26. PubMed PMID: 30290303; PubMed Central PMCID: PMC6171091.

6: Rafii MS, Tuszynski MH, Thomas RG, Barba D, Brewer JB, Rissman RA, Siffert J, Aisen PS; AAV2-NGF Study Team. Adeno-Associated Viral Vector (Serotype 2)-Nerve Growth Factor for Patients With Alzheimer Disease: A Randomized Clinical Trial. JAMA Neurol. 2018 Jul 1;75(7):834-841. doi: 10.1001/jamaneurol.2018.0233. PubMed PMID: 29582053; PubMed Central PMCID: PMC5885277.

7: Perkins BA, Caskey CT, Brar P, Dec E, Karow DS, Kahn AM, Hou YC, Shah N, Boeldt D, Coughlin E, Hands G, Lavrenko V, Yu J, Procko A, Appis J, Dale AM, Guo L, Jönsson TJ, Wittmann BM, Bartha I, Ramakrishnan S, Bernal A, Brewer JB, Brewerton S, Biggs WH, Turpaz Y, Venter JC. Precision medicine screening using whole-genome sequencing and advanced imaging to identify disease risk in adults. Proc Natl Acad Sci U S A. 2018 Apr 3;115(14):3686-3691. doi: 10.1073/pnas.1706096114. Epub 2018 Mar 19. PubMed PMID: 29555771; PubMed Central PMCID: PMC5889622.

8: Tan CH, Fan CC, Mormino EC, Sugrue LP, Broce IJ, Hess CP, Dillon WP, Bonham LW, Yokoyama JS, Karch CM, Brewer JB, Rabinovici GD, Miller BL, Schellenberg GD, Kauppi K, Feldman HA, Holland D, McEvoy LK, Hyman BT, Bennett DA, Andreassen OA, Dale AM, Desikan RS; Alzheimer’s Disease Neuroimaging Initiative. Polygenic hazard score: an enrichment marker for Alzheimer's associated amyloid and tau deposition. Acta Neuropathol. 2018 Jan;135(1):85-93. doi: 10.1007/s00401-017-1789-4. Epub 2017 Nov 24. PubMed PMID: 29177679; PubMed Central PMCID: PMC5758038.

9: Reas ET, Hagler DJ Jr, White NS, Kuperman JM, Bartsch H, Cross K, Loi RQ, Balachandra AR, Meloy MJ, Wierenga CE, Galasko D, Brewer JB, Dale AM, McEvoy LK. Sensitivity of restriction spectrum imaging to memory and neuropathology in Alzheimer's disease. Alzheimers Res Ther. 2017 Aug 2;9(1):55. doi: 10.1186/s13195-017-0281-7. PubMed PMID: 28764771; PubMed Central PMCID: PMC5539622.

10: Relkin NR, Thomas RG, Rissman RA, Brewer JB, Rafii MS, van Dyck CH, Jack CR, Sano M, Knopman DS, Raman R, Szabo P, Gelmont DM, Fritsch S, Aisen PS; Alzheimer's Disease Cooperative Study. A phase 3 trial of IV immunoglobulin for Alzheimer disease. Neurology. 2017 May 2;88(18):1768-1775. doi: 10.1212/WNL.0000000000003904. Epub 2017 Apr 5. PubMed PMID: 28381506; PubMed Central PMCID: PMC5409846.

11: Seibert TM, Karunamuni R, Kaifi S, Burkeen J, Connor M, Krishnan AP, White NS, Farid N, Bartsch H, Murzin V, Nguyen TT, Moiseenko V, Brewer JB, McDonald CR, Dale AM, Hattangadi-Gluth JA. Cerebral Cortex Regions Selectively Vulnerable to Radiation Dose-Dependent Atrophy. Int J Radiat Oncol Biol Phys. 2017 Apr 1;97(5):910-918. doi: 10.1016/j.ijrobp.2017.01.005. Epub 2017 Jan 6. PubMed PMID: 28333012; PubMed Central PMCID: PMC5403140.

12: Desikan RS, Fan CC, Wang Y, Schork AJ, Cabral HJ, Cupples LA, Thompson WK, Besser L, Kukull WA, Holland D, Chen CH, Brewer JB, Karow DS, Kauppi K, Witoelar A, Karch CM, Bonham LW, Yokoyama JS, Rosen HJ, Miller BL, Dillon WP, Wilson DM, Hess CP, Pericak-Vance M, Haines JL, Farrer LA, Mayeux R, Hardy J, Goate AM, Hyman BT, Schellenberg GD, McEvoy LK, Andreassen OA, Dale AM. Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score. PLoS Med. 2017 Mar 21;14(3):e1002258. doi: 10.1371/journal.pmed.1002258. eCollection 2017 Mar. Erratum in: PLoS Med. 2017 Mar 28;14 (3):e1002289. PubMed PMID: 28323831; PubMed Central PMCID: PMC5360219.

13: Gimbel SI, Brewer JB, Maril A. I know I've seen you before: Distinguishing recent-single-exposure-based familiarity from pre-existing familiarity. Brain Res. 2017 Mar 1;1658:11-24. doi: 10.1016/j.brainres.2017.01.007. Epub 2017 Jan 7. PubMed PMID: 28073651; PubMed Central PMCID: PMC5867277.

14: Seibert TM, Karunamuni R, Bartsch H, Kaifi S, Krishnan AP, Dalia Y, Burkeen J, Murzin V, Moiseenko V, Kuperman J, White NS, Brewer JB, Farid N, McDonald CR, Hattangadi-Gluth JA. Radiation Dose-Dependent Hippocampal Atrophy Detected With Longitudinal Volumetric Magnetic Resonance Imaging. Int J Radiat Oncol Biol Phys. 2017 Feb 1;97(2):263-269. doi: 10.1016/j.ijrobp.2016.10.035. Epub 2016 Oct 31. PubMed PMID: 28068234; PubMed Central PMCID: PMC5267344.

15: Ferrari R, Wang Y, Vandrovcova J, Guelfi S, Witeolar A, Karch CM, Schork AJ, Fan CC, Brewer JB; International FTD-Genomics Consortium (IFGC),; International Parkinson's Disease Genomics Consortium (IPDGC),; International Genomics of Alzheimer's Project (IGAP),, Momeni P, Schellenberg GD, Dillon WP, Sugrue LP, Hess CP, Yokoyama JS, Bonham LW, Rabinovici GD, Miller BL, Andreassen OA, Dale AM, Hardy J, Desikan RS. Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases. J Neurol Neurosurg Psychiatry. 2017 Feb;88(2):152-164. doi: 10.1136/jnnp-2016-314411. Epub 2016 Nov 29. PubMed PMID: 27899424; PubMed Central PMCID: PMC5237405.

16: Gelmont D, Thomas RG, Britt J, Dyck-Jones JA, Doralt J, Fritsch S, Brewer JB, Rissman RA, Aisen P. Demonstration of safety of intravenous immunoglobulin in geriatric patients in a long-term, placebo-controlled study of Alzheimer's disease. Alzheimers Dement (N Y). 2016 Jun 21;2(2):131-139. doi: 10.1016/j.trci.2016.06.003. eCollection 2016 Jun. PubMed PMID: 29067300; PubMed Central PMCID: PMC5644268.

17: Yokoyama JS, Wang Y, Schork AJ, Thompson WK, Karch CM, Cruchaga C, McEvoy LK, Witoelar A, Chen CH, Holland D, Brewer JB, Franke A, Dillon WP, Wilson DM, Mukherjee P, Hess CP, Miller Z, Bonham LW, Shen J, Rabinovici GD, Rosen HJ, Miller BL, Hyman BT, Schellenberg GD, Karlsen TH, Andreassen OA, Dale AM, Desikan RS; Alzheimer’s Disease Neuroimaging Initiative. Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease. JAMA Neurol. 2016 Jun 1;73(6):691-7. doi: 10.1001/jamaneurol.2016.0150. PubMed PMID: 27088644; PubMed Central PMCID: PMC4905783.

18: Karunamuni R, Bartsch H, White NS, Moiseenko V, Carmona R, Marshall DC, Seibert TM, McDonald CR, Farid N, Krishnan A, Kuperman J, Mell L, Brewer JB, Dale AM, Hattangadi-Gluth JA. Dose-Dependent Cortical Thinning After Partial Brain Irradiation in High-Grade Glioma. Int J Radiat Oncol Biol Phys. 2016 Feb 1;94(2):297-304. doi: 10.1016/j.ijrobp.2015.10.026. Epub 2015 Oct 21. PubMed PMID: 26853338; PubMed Central PMCID: PMC4747044.

19: Rafii MS, Wishnek H, Brewer JB, Donohue MC, Ness S, Mobley WC, Aisen PS, Rissman RA. The down syndrome biomarker initiative (DSBI) pilot: proof of concept for deep phenotyping of Alzheimer's disease biomarkers in down syndrome. Front Behav Neurosci. 2015 Sep 14;9:239. doi: 10.3389/fnbeh.2015.00239. eCollection 2015. PubMed PMID: 26441570; PubMed Central PMCID: PMC4568340.

20: Turner RS, Thomas RG, Craft S, van Dyck CH, Mintzer J, Reynolds BA, Brewer JB, Rissman RA, Raman R, Aisen PS; Alzheimer's Disease Cooperative Study. A randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer disease. Neurology. 2015 Oct 20;85(16):1383-91. doi: 10.1212/WNL.0000000000002035. Epub 2015 Sep 11. PubMed PMID: 26362286; PubMed Central PMCID: PMC4626244.

21: Desikan RS, Schork AJ, Wang Y, Thompson WK, Dehghan A, Ridker PM, Chasman DI, McEvoy LK, Holland D, Chen CH, Karow DS, Brewer JB, Hess CP, Williams J, Sims R, O'Donovan MC, Choi SH, Bis JC, Ikram MA, Gudnason V, DeStefano AL, van der Lee SJ, Psaty BM, van Duijn CM, Launer L, Seshadri S, Pericak-Vance MA, Mayeux R, Haines JL, Farrer LA, Hardy J, Ulstein ID, Aarsland D, Fladby T, White LR, Sando SB, Rongve A, Witoelar A, Djurovic S, Hyman BT, Snaedal J, Steinberg S, Stefansson H, Stefansson K, Schellenberg GD, Andreassen OA, Dale AM; Inflammation working group, IGAP and DemGene Investigators. Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease. Circulation. 2015 Jun 9;131(23):2061-2069. doi: 10.1161/CIRCULATIONAHA.115.015489. Epub 2015 Apr 10. PubMed PMID: 25862742; PubMed Central PMCID: PMC4677995.

22: Desikan RS, Schork AJ, Wang Y, Witoelar A, Sharma M, McEvoy LK, Holland D, Brewer JB, Chen CH, Thompson WK, Harold D, Williams J, Owen MJ, O'Donovan MC, Pericak-Vance MA, Mayeux R, Haines JL, Farrer LA, Schellenberg GD, Heutink P, Singleton AB, Brice A, Wood NW, Hardy J, Martinez M, Choi SH, DeStefano A, Ikram MA, Bis JC, Smith A, Fitzpatrick AL, Launer L, van Duijn C, Seshadri S, Ulstein ID, Aarsland D, Fladby T, Djurovic S, Hyman BT, Snaedal J, Stefansson H, Stefansson K, Gasser T, Andreassen OA, Dale AM; ADNI, ADGC, GERAD, CHARGE and IPDGC Investigators. Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus. Mol Psychiatry. 2015 Dec;20(12):1588-95. doi: 10.1038/mp.2015.6. Epub 2015 Feb 17. PubMed PMID: 25687773; PubMed Central PMCID: PMC4539304.

23: Reas ET, Brewer JB. Mean signal and response time influences on multivoxel signals of contextual retrieval in the medial temporal lobe. Brain Behav. 2015 Feb;5(2):e00302. doi: 10.1002/brb3.302. Epub 2014 Dec 24. PubMed PMID: 25646149; PubMed Central PMCID: PMC4312925.

24: Brezova V, Moen KG, Skandsen T, Vik A, Brewer JB, Salvesen O, Håberg AK. Prospective longitudinal MRI study of brain volumes and diffusion changes during the first year after moderate to severe traumatic brain injury. Neuroimage Clin. 2014 Mar 28;5:128-40. doi: 10.1016/j.nicl.2014.03.012. eCollection 2014. PubMed PMID: 25068105; PubMed Central PMCID: PMC4110353.

25: Gimbel SI, Brewer JB. Elaboration versus suppression of cued memories: influence of memory recall instruction and success on parietal lobe, default network, and hippocampal activity. PLoS One. 2014 Feb 19;9(2):e89037. doi: 10.1371/journal.pone.0089037. eCollection 2014. PubMed PMID: 24586492; PubMed Central PMCID: PMC3929625.

26: Desikan RS, Thompson WK, Holland D, Hess CP, Brewer JB, Zetterberg H, Blennow K, Andreassen OA, McEvoy LK, Hyman BT, Dale AM; Alzheimer’s Disease Neuroimaging Initiative Group. The role of clusterin in amyloid-β-associated neurodegeneration. JAMA Neurol. 2014 Feb;71(2):180-7. doi: 10.1001/jamaneurol.2013.4560. PubMed PMID: 24378367; PubMed Central PMCID: PMC4118752.

27: Rafii MS, Taylor CS, Kim HT, Desikan RS, Fleisher AS, Katibian D, Brewer JB, Dale AM, Aisen PS. Neuropsychiatric symptoms and regional neocortical atrophy in mild cognitive impairment and Alzheimer's disease. Am J Alzheimers Dis Other Demen. 2014 Mar;29(2):159-65. doi: 10.1177/1533317513507373. Epub 2013 Oct 27. PubMed PMID: 24164929; PubMed Central PMCID: PMC5351414.

28: Desikan RS, Thompson WK, Holland D, Hess CP, Brewer JB, Zetterberg H, Blennow K, Andreassen OA, McEvoy LK, Hyman BT, Dale AM; Alzheimer’s Disease Neuroimaging Initiative. Heart fatty acid binding protein and Aβ-associated Alzheimer's neurodegeneration. Mol Neurodegener. 2013 Oct 2;8:39. doi: 10.1186/1750-1326-8-39. PubMed PMID: 24088526; PubMed Central PMCID: PMC3850652.

29: Reas ET, Brewer JB. Imbalance of incidental encoding across tasks: an explanation for non-memory-related hippocampal activations? J Exp Psychol Gen. 2013 Nov;142(4):1171-9. doi: 10.1037/a0033461. Epub 2013 Jun 17. PubMed PMID: 23773160; PubMed Central PMCID: PMC3834009.

30: Desikan RS, Rafii MS, Brewer JB, Hess CP. An expanded role for neuroimaging in the evaluation of memory impairment. AJNR Am J Neuroradiol. 2013 Nov-Dec;34(11):2075-82. doi: 10.3174/ajnr.A3644. Epub 2013 Jun 13. PubMed PMID: 23764728; PubMed Central PMCID: PMC4077712.

31: McEvoy LK, Brewer JB. Biomarkers for the clinical evaluation of the cognitively impaired elderly: amyloid is not enough. Imaging Med. 2012 Jun;4(3):343-357. PubMed PMID: 23420460; PubMed Central PMCID: PMC3573528.

32: Reas ET, Brewer JB. Effortful retrieval reduces hippocampal activity and impairs incidental encoding. Hippocampus. 2013 May;23(5):367-79. doi: 10.1002/hipo.22096. Epub 2013 Feb 2. PubMed PMID: 23378272; PubMed Central PMCID: PMC4049294.

33: Reas ET, Gimbel SI, Hales JB, Brewer JB. Erratum: search-related suppression of hippocampus and default network activity during associative memory retrieval. Front Hum Neurosci. 2013 Jan 24;7:2. doi: 10.3389/fnhum.2013.00002. eCollection 2013. PubMed PMID: 23355818; PubMed Central PMCID: PMC3553375.

34: Hales JB, Brewer JB. Parietal and frontal contributions to episodic encoding of location. Behav Brain Res. 2013 Apr 15;243:16-20. doi: 10.1016/j.bbr.2012.12.048. Epub 2013 Jan 4. PubMed PMID: 23295390; PubMed Central PMCID: PMC3593964.

35: Reas ET, Brewer JB. Retrieval search and strength evoke dissociable brain activity during episodic memory recall. J Cogn Neurosci. 2013 Feb;25(2):219-33. doi: 10.1162/jocn_a_00335. Epub 2012 Nov 28. PubMed PMID: 23190328; PubMed Central PMCID: PMC4091972.

36: Desikan RS, McEvoy LK, Holland D, Thompson WK, Brewer JB, Aisen PS, Andreassen OA, Hyman BT, Sperling RA, Dale AM; Alzheimer's Disease Neuroimaging Initiative. Apolipoprotein E epsilon4 does not modulate amyloid-β-associated neurodegeneration in preclinical Alzheimer disease. AJNR Am J Neuroradiol. 2013 Mar;34(3):505-10. doi: 10.3174/ajnr.A3267. Epub 2012 Sep 13. PubMed PMID: 22976236; PubMed Central PMCID: PMC4041629.

37: Desikan RS, McEvoy LK, Thompson WK, Holland D, Brewer JB, Aisen PS, Sperling RA, Dale AM; Alzheimer’s Disease Neuroimaging Initiative. Amyloid-β--associated clinical decline occurs only in the presence of elevated P-tau. Arch Neurol. 2012 Jun;69(6):709-13. doi: 10.1001/archneurol.2011.3354. PubMed PMID: 22529247; PubMed Central PMCID: PMC3423526.

38: Hales JB, Brewer JB. The path to memory is guided by strategy: distinct networks are engaged in associative encoding under visual and verbal strategy and influence memory performance in healthy and impaired individuals. J Cogn Neurosci. 2012 Jun;24(6):1398-410. doi: 10.1162/jocn_a_00220. Epub 2012 Mar 5. PubMed PMID: 22390467; PubMed Central PMCID: PMC5889914.

39: Seibert TM, Murphy EA, Kaestner EJ, Brewer JB. Interregional correlations in Parkinson disease and Parkinson-related dementia with resting functional MR imaging. Radiology. 2012 Apr;263(1):226-34. doi: 10.1148/radiol.12111280. Epub 2012 Feb 27. PubMed PMID: 22371611; PubMed Central PMCID: PMC3309803.

40: Reas ET, Gimbel SI, Hales JB, Brewer JB. Search-Related Suppression of Hippocampus and Default Network Activity during Associative Memory Retrieval. Front Hum Neurosci. 2011 Oct 30;5:112. doi: 10.3389/fnhum.2011.00112. eCollection 2011. PubMed PMID: 22046159; PubMed Central PMCID: PMC3202230.

41: Desikan RS, McEvoy LK, Thompson WK, Holland D, Roddey JC, Blennow K, Aisen PS, Brewer JB, Hyman BT, Dale AM; Alzheimer’s Disease Neuroimaging Initiative. Amyloid-β associated volume loss occurs only in the presence of phospho-tau. Ann Neurol. 2011 Oct;70(4):657-61. doi: 10.1002/ana.22509. Epub 2011 Oct 14. PubMed PMID: 22002658; PubMed Central PMCID: PMC3368003.

42: Heister D, Brewer JB, Magda S, Blennow K, McEvoy LK; Alzheimer's Disease Neuroimaging Initiative. Predicting MCI outcome with clinically available MRI and CSF biomarkers. Neurology. 2011 Oct 25;77(17):1619-28. doi: 10.1212/WNL.0b013e3182343314. Epub 2011 Oct 12. PubMed PMID: 21998317; PubMed Central PMCID: PMC3198979.

43: Seibert TM, Majid DS, Aron AR, Corey-Bloom J, Brewer JB. Stability of resting fMRI interregional correlations analyzed in subject-native space: a one-year longitudinal study in healthy adults and premanifest Huntington's disease. Neuroimage. 2012 Feb 1;59(3):2452-63. doi: 10.1016/j.neuroimage.2011.08.105. Epub 2011 Sep 10. PubMed PMID: 21945695; PubMed Central PMCID: PMC3254727.

44: Murphy EA, Roddey JC, McEvoy LK, Holland D, Hagler DJ Jr, Dale AM, Brewer JB; Alzheimer’s Disease Neuroimaging Initiative. CETP polymorphisms associate with brain structure, atrophy rate, and Alzheimer's disease risk in an APOE-dependent manner. Brain Imaging Behav. 2012 Mar;6(1):16-26. doi: 10.1007/s11682-011-9137-0. PubMed PMID: 21892657; PubMed Central PMCID: PMC4305449.

45: Seibert TM, Brewer JB. Default network correlations analyzed on native surfaces. J Neurosci Methods. 2011 Jun 15;198(2):301-11. doi: 10.1016/j.jneumeth.2011.04.010. Epub 2011 Apr 14. PubMed PMID: 21514321; PubMed Central PMCID: PMC3111080.

46: McEvoy LK, Holland D, Hagler DJ Jr, Fennema-Notestine C, Brewer JB, Dale AM; Alzheimer's Disease Neuroimaging Initiative. Mild cognitive impairment: baseline and longitudinal structural MR imaging measures improve predictive prognosis. Radiology. 2011 Jun;259(3):834-43. doi: 10.1148/radiol.11101975. Epub 2011 Apr 6. PubMed PMID: 21471273; PubMed Central PMCID: PMC3099042.

47: Gimbel SI, Brewer JB. Reaction time, memory strength, and fMRI activity during memory retrieval: Hippocampus and default network are differentially responsive during recollection and familiarity judgments. Cogn Neurosci. 2011 Mar;2(1):19-23. PubMed PMID: 21278912; PubMed Central PMCID: PMC3026441.

48: Hales JB, Brewer JB. The timing of associative memory formation: frontal lobe and anterior medial temporal lobe activity at associative binding predicts memory. J Neurophysiol. 2011 Apr;105(4):1454-63. doi: 10.1152/jn.00902.2010. Epub 2011 Jan 19. PubMed PMID: 21248058; PubMed Central PMCID: PMC3075291.

49: Rafii MS, Brewer JB. Functional brain imaging in the clinical assessment of consciousness. PLoS Biol. 2010 Nov 30;8(11):e1000548. doi: 10.1371/journal.pbio.1000548. PubMed PMID: 21151340; PubMed Central PMCID: PMC2994656.

50: Seibert TM, Gimbel SI, Hagler DJ Jr, Brewer JB. Parietal activity in episodic retrieval measured by fMRI and MEG. Neuroimage. 2011 Mar 15;55(2):788-93. doi: 10.1016/j.neuroimage.2010.11.078. Epub 2010 Dec 4. PubMed PMID: 21134473; PubMed Central PMCID: PMC3035726.

51: McEvoy LK, Brewer JB. Quantitative structural MRI for early detection of Alzheimer's disease. Expert Rev Neurother. 2010 Nov;10(11):1675-88. doi: 10.1586/ern.10.162. Review. PubMed PMID: 20977326; PubMed Central PMCID: PMC3182103.

52: Karow DS, McEvoy LK, Fennema-Notestine C, Hagler DJ Jr, Jennings RG, Brewer JB, Hoh CK, Dale AM; Alzheimer's Disease Neuroimaging Initiative. Relative capability of MR imaging and FDG PET to depict changes associated with prodromal and early Alzheimer disease. Radiology. 2010 Sep;256(3):932-42. doi: 10.1148/radiol.10091402. PubMed PMID: 20720076; PubMed Central PMCID: PMC2923729.

53: McEvoy LK, Edland SD, Holland D, Hagler DJ Jr, Roddey JC, Fennema-Notestine C, Salmon DP, Koyama AK, Aisen PS, Brewer JB, Dale AM; Alzheimerʼs Disease Neuroimaging Initiative. Neuroimaging enrichment strategy for secondary prevention trials in Alzheimer disease. Alzheimer Dis Assoc Disord. 2010 Jul-Sep;24(3):269-77. doi: 10.1097/WAD.0b013e3181d1b814. PubMed PMID: 20683184; PubMed Central PMCID: PMC2929320.

54: Hales JB, Brewer JB. Activity in the hippocampus and neocortical working memory regions predicts successful associative memory for temporally discontiguous events. Neuropsychologia. 2010 Sep;48(11):3351-9. doi: 10.1016/j.neuropsychologia.2010.07.025. Epub 2010 Aug 1. PubMed PMID: 20667491; PubMed Central PMCID: PMC2929120.

55: Murphy EA, Holland D, Donohue M, McEvoy LK, Hagler DJ Jr, Dale AM, Brewer JB; Alzheimer's Disease Neuroimaging Initiative. Six-month atrophy in MTL structures is associated with subsequent memory decline in elderly controls. Neuroimage. 2010 Dec;53(4):1310-7. doi: 10.1016/j.neuroimage.2010.07.016. Epub 2010 Jul 13. PubMed PMID: 20633660; PubMed Central PMCID: PMC2939234.

56: Seibert TM, Hagler DJ Jr, Brewer JB. Early parietal response in episodic retrieval revealed with MEG. Hum Brain Mapp. 2011 Feb;32(2):171-81. doi: 10.1002/hbm.21014. PubMed PMID: 20623759; PubMed Central PMCID: PMC3107600.

57: Fjell AM, Walhovd KB, Fennema-Notestine C, McEvoy LK, Hagler DJ, Holland D, Brewer JB, Dale AM; Alzheimer's Disease Neuroimaging Initiative. CSF biomarkers in prediction of cerebral and clinical change in mild cognitive impairment and Alzheimer's disease. J Neurosci. 2010 Feb 10;30(6):2088-101. doi: 10.1523/JNEUROSCI.3785-09.2010. PubMed PMID: 20147537; PubMed Central PMCID: PMC2828879.

58: Pitts MA, Martínez A, Brewer JB, Hillyard SA. Early stages of figure-ground segregation during perception of the face-vase. J Cogn Neurosci. 2011 Apr;23(4):880-95. doi: 10.1162/jocn.2010.21438. Epub 2010 Feb 10. PubMed PMID: 20146604; PubMed Central PMCID: PMC3071650.

59: Fjell AM, Walhovd KB, Fennema-Notestine C, McEvoy LK, Hagler DJ, Holland D, Blennow K, Brewer JB, Dale AM; Alzheimer's Disease Neuroimaging Initiative. Brain atrophy in healthy aging is related to CSF levels of Aβ1-42. Cereb Cortex. 2010 Sep;20(9):2069-79. doi: 10.1093/cercor/bhp279. Epub 2010 Jan 4. PubMed PMID: 20051356; PubMed Central PMCID: PMC3025722.

60: Holland D, Brewer JB, Hagler DJ, Fennema-Notestine C, Dale AM; Alzheimer's Disease Neuroimaging Initiative. Subregional neuroanatomical change as a biomarker for Alzheimer's disease. Proc Natl Acad Sci U S A. 2009 Dec 8;106(49):20954-9. Erratum in: Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6551. Fenema-Notestine, Christine [corrected to Fennema-Notestine, Christine]. PubMed PMID: 19996185; PubMed Central PMCID: PMC2791580.

61: Fjell AM, Walhovd KB, Fennema-Notestine C, McEvoy LK, Hagler DJ, Holland D, Brewer JB, Dale AM. One-year brain atrophy evident in healthy aging. J Neurosci. 2009 Dec 2;29(48):15223-31. doi: 10.1523/JNEUROSCI.3252-09.2009. PubMed PMID: 19955375; PubMed Central PMCID: PMC2827793.

62: Fleisher AS, Donohue M, Chen K, Brewer JB, Aisen PS; Alzheimer's Disease Neuroimaging Initiative. Applications of neuroimaging to disease-modification trials in Alzheimer's disease. Behav Neurol. 2009;21(1):129-36. doi: 10.3233/BEN-2009-0241. Review. PubMed PMID: 19847051; PubMed Central PMCID: PMC5444278.

63: Brewer JB. Fully-automated volumetric MRI with normative ranges: translation to clinical practice. Behav Neurol. 2009;21(1):21-8. doi: 10.3233/BEN-2009-0226. Review. PubMed PMID: 19847042; PubMed Central PMCID: PMC5444284.

64: McDonald CR, McEvoy LK, Gharapetian L, Fennema-Notestine C, Hagler DJ Jr, Holland D, Koyama A, Brewer JB, Dale AM; Alzheimer's Disease Neuroimaging Initiative. Regional rates of neocortical atrophy from normal aging to early Alzheimer disease. Neurology. 2009 Aug 11;73(6):457-65. doi: 10.1212/WNL.0b013e3181b16431. PubMed PMID: 19667321; PubMed Central PMCID: PMC2727145.

65: Kovacevic S, Rafii MS, Brewer JB; Alzheimer's Disease Neuroimaging Initiative. High-throughput, fully automated volumetry for prediction of MMSE and CDR decline in mild cognitive impairment. Alzheimer Dis Assoc Disord. 2009 Apr-Jun;23(2):139-45. doi: 10.1097/WAD.0b013e318192e745. PubMed PMID: 19474571; PubMed Central PMCID: PMC2688740.

66: Israel SL, Seibert TM, Black ML, Brewer JB. Going their separate ways: dissociation of hippocampal and dorsolateral prefrontal activation during episodic retrieval and post-retrieval processing. J Cogn Neurosci. 2010 Mar;22(3):513-25. doi: 10.1162/jocn.2009.21198. PubMed PMID: 19301994.

67: McEvoy LK, Fennema-Notestine C, Roddey JC, Hagler DJ Jr, Holland D, Karow DS, Pung CJ, Brewer JB, Dale AM; Alzheimer's Disease Neuroimaging Initiative. Alzheimer disease: quantitative structural neuroimaging for detection and prediction of clinical and structural changes in mild cognitive impairment. Radiology. 2009 Apr;251(1):195-205. doi: 10.1148/radiol.2511080924. Epub 2009 Feb 6. PubMed PMID: 19201945; PubMed Central PMCID: PMC2663582.

68: Brewer JB, Magda S, Airriess C, Smith ME. Fully-automated quantification of regional brain volumes for improved detection of focal atrophy in Alzheimer disease. AJNR Am J Neuroradiol. 2009 Mar;30(3):578-80. doi: 10.3174/ajnr.A1402. Epub 2008 Dec 26. PubMed PMID: 19112065; PubMed Central PMCID: PMC5947999.

69: Hales JB, Israel SL, Swann NC, Brewer JB. Dissociation of frontal and medial temporal lobe activity in maintenance and binding of sequentially presented paired associates. J Cogn Neurosci. 2009 Jul;21(7):1244-54. doi: 10.1162/jocn.2009.21096. PubMed PMID: 18752401; PubMed Central PMCID: PMC2674124.

70: Gold JJ, Smith CN, Bayley PJ, Shrager Y, Brewer JB, Stark CE, Hopkins RO, Squire LR. Item memory, source memory, and the medial temporal lobe: concordant findings from fMRI and memory-impaired patients. Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9351-6. Epub 2006 Jun 2. PubMed PMID: 16751272; PubMed Central PMCID: PMC1482613.

71: Brewer JB, Moghekar A. Imaging the medial temporal lobe: exploring new dimensions. Trends Cogn Sci. 2002 May 1;6(5):217-223. PubMed PMID: 11983585.

72: Golby AJ, Poldrack RA, Brewer JB, Spencer D, Desmond JE, Aron AP, Gabrieli JD. Material-specific lateralization in the medial temporal lobe and prefrontal cortex during memory encoding. Brain. 2001 Sep;124(Pt 9):1841-54. PubMed PMID: 11522586.

73: Fernández G, Brewer JB, Zhao Z, Glover GH, Gabrieli JD. Level of sustained entorhinal activity at study correlates with subsequent cued-recall performance: a functional magnetic resonance imaging study with high acquisition rate. Hippocampus. 1999;9(1):35-44. PubMed PMID: 10088898.

74: Gabrieli JD, Brewer JB, Poldrack RA. Images of medial temporal lobe functions in human learning and memory. Neurobiol Learn Mem. 1998 Jul-Sep;70(1-2):275-83. Review. PubMed PMID: 9753602.

75: Brewer JB, Zhao Z, Desmond JE, Glover GH, Gabrieli JD. Making memories: brain activity that predicts how well visual experience will be remembered. Science. 1998 Aug 21;281(5380):1185-7. PubMed PMID: 9712581.

76: Brewer JB, Gabrieli JD. Focusing in on the medial temporal lobe. Mol Psychiatry. 1997 Oct-Nov;2(6):430-1, 427-8. PubMed PMID: 9399679.

77: Gabrieli JD, Brewer JB, Desmond JE, Glover GH. Separate neural bases of two fundamental memory processes in the human medial temporal lobe. Science. 1997 Apr 11;276(5310):264-6. PubMed PMID: 9092477.