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Dore Lab Publications


A.Q. Pham, K. Dore. (2022) Novel approaches to increase synaptic resilience as potential treatments for Alzheimer’s disease. Seminars in Cell and Developmental Biology. Published online on 3/31/2022.

Lordén, G., Wozniak, J.M., Doré, K. et al. Enhanced activity of Alzheimer disease-associated variant of protein kinase Cα drives cognitive decline in a mouse model. Nat Commun 13, 7200 (2022).

K. Dore1, Z. Carrico, S. Alfonso, M. Marino, K. Koymans, H. Kessels, R. Malinow. (2021) PSD-95 protects synapses from β-amyloid. Cell Reports, 35, 109194. 1- Corresponding author

K. Dore1 and Roberto Malinow. (2021) Elevated PSD-95 blocks ion-flux independent LTD: a new role for PSD-95 in synaptic plasticity. Neuroscience, 456:43-49. doi: 10.1016/j.neuroscience.2020.02.020. Epub 2020 Feb 28. 1- Corresponding author

K. Dore, Y. Pao, J. S. Lopez, S. Aronson, H. Zhan, S. Ghosh, S. Merrill, A. M. Zador, R. Malinow, J. M. Kebschull. (2020) SYNPLA, a method for identifying synapses displaying plasticity after learning. Proc Natl Acad Sci U S A., 117 (6) 3214-3219,

K. Sapoka, K. Dore, K. Tang, M. Irvine, G. Fang, E.S. Burnell, R. Malinow, D.E. Jane, D.T. Monaghan. (2019) The NMDA receptor intracellular C-terminal domains reciprocally interact with allosteric modulators. Biochem Pharmacol., 159:140-153.

K. Dore, I.S. Stein, J.A. Brock, P.E Castillo, K. Zito, P.J. Sjöström. (2017) Unconventional NMDA receptor signaling. Journal of Neuroscience 37 (45), 10800-10807.

K. Dore, J. Aow, R. Malinow. (2016) The emergence of NMDA receptor metabotropic function: insights from imaging. Frontiers in synaptic neuroscience. 8:20. doi: 10.3389/fnsyn.2016.00020.

K. Dore, J. Aow, R. Malinow. (2015) Agonist binding to the NMDA receptor drives movement of its cytoplasmic domain without ion flow. Proc Natl Acad Sci U S A. 112(47): 14705-14710.

J. Aow1, K. Dore1, R. Malinow. (2015) Conformational signaling required for synaptic plasticity by the NMDAR complex. Proc Natl Acad Sci U S A. 112(47): 14711-14716. 1- Authors contributed equally

L-C.L. Tsai, L. Xie, K. Dore, L. Xie, J.C. Del Rio, C.C. King, G. Martinez-Ariza, C. Hulme, R. Malinow, P.E. Bourne, A.C. Newton. (2015) Zeta Inhibitory Peptide Disrupts Electrostatic Interactions That Maintain Atypical Protein Kinase C in Its Active Conformation on the Scaffold p62. Journal of Biological Chemistry. 290 (36), 21845-21856

K. Dore, S. Labrecque, C. Tardif, P. De Koninck. (2014) FRET-FLIM Investigation of PSD95-NMDA Receptor Interaction in Dendritic Spines; Control by Calpain, CaMKII and Src Family Kinase. PloS one. 9(11):e112170.

J.L. Swift, A.G. Godin, K. Dore, L. Freland, N. Bouchard, C. Nimmo, M. Sergeev, Y. De Koninck, P.W. Wiseman, J.M. Beaulieu (2011) Quantification of receptor tyrosine kinase transactivation through direct dimerization and surface density measurements in single cells. Proc Natl Acad Sci U S A, 108(17):7016-21.