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Department of Neurosciences Department of Neurosciences
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Research Studies: Multiple System Atrophy

Currently Enrolling Studies

Integrating Co-Pathology and Neuroinflammation Profiling for Early Diagnosis and Patient Stratification

Help advance research on early diagnosis of Parkinson’s disease and related disorders. This study is evaluating whether proteins in biological samples can help distinguish Parkinson’s disease and identify early stages.

There is one in-person visit at UC San Diego (about 2.5 to 4 hours), which may include:

  • Questionnaires and neurological exam
  • Blood pressure measurement
  • Blood draw
  • Small skin biopsy Compensation Up to $50 for parking or transportation
Who Can Participate
  • Individuals with PD, MSA, CBS, or PSP
  • Healthy adults

Contact us at 858-246-2505 or MDCResearchStudies@health.ucsd.edu


Ongoing Studies Currently Closed to Enrollment

TEVA: A Multi-centered, Double-blind, Randomized, Placebo-controlled, Parallel Group Phase 2 Study of TEV-56286 for the Treatment of Patients with Multiple System Atrophy

  • To determine if an oral investigational drug can stabilize, limit or slow the worsening of MSA symptoms and to determine how safe and well tolerated this drug is in adults with MSA.
  • Participation in this research study will involve 7 visits to the research site and will last about 56 weeks.
  • Male or female ≥30 years old with “clinically possible” or “clinically probable” MSA and able to ambulate at least 10 meters without the assistance of another person.

RT-QuIC: Premortem detection of misfolded proteins in biopsy skin samples and saliva in parkinsonism

  • The purpose of this study is to analyze the effectiveness of a procedure called a skin punch biopsy to lead to an earlier diagnosis. Skin biopsy could be a useful way to diagnose and measure the severity of these conditions.

  • Participation in this study would involve one visit lasting about 3 hours for a physical exam, questionnaires, a memory test, a punch skin biopsy, and blood draw.

A Randomized Double-Blind, Placebo-Controlled Study of ATH434-201 to determine efficacy, safety and tolerability in patients with MSA (2)

  • To assess the efficacy of the study drug (ATH434) in patients with MSA
  • To assess whether the study drug (ATH434) is save and tolerable in patients with MSA
  • Currently enrolling adults aged 30 to 75 with a confirmed diagnosis of MSA

 

 

 

Questions?

For more information about our center's research studies, contact our Clinical Research Manager:

Jo Talledo Benrubi | atalledo@health.ucsd.edu | (858) 246-2505
Or reach our research team at MDCResearchStudies@health.ucsd.edu