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About Shiley-Marcos Alzheimer's Disease Research Center 

The Shiley-Marcos Alzheimer's Disease Research Center (SMADRC) is in the Department of Neurosciences at the University of California, San Diego. We are one of 31 university-based sites funded by the National Institute of Health (NIH) National Institute on Aging (NIA) to collect and contribute data to the National Alzheimer's Coordinating Center (NACC) to faciliate collaborative research. 

What We Do

Our center conducts research studies dedicated to understanding the causes, clinical features, and treatments for Alzheimer's disease (AD) and related memory disorders.

Our Mission

  • Carry out research into the causes, treatment, and prevention of AD
  • Act as a local and national resource by providing research subjects, data, and materials to researchers in AD and related disorders
  • Provide training opportunities for clinicians and researchers
  • Educate professionals and the community regarding AD
  • Provide outreach to the diverse San Diego community regarding diagnosis, treatment, and care for persons with AD

Our Research

We follow approximately 350 seniors with AD or a related dementia and 150 age-matched participants with no memory problems annually.

The Shiley-Marcos ADRC is also one of 35 nationwide university medical centers designated to carry out clinical trials coordinated by the Alzheimer's Disease Cooperative Study, which was created by the National Institute on Aging. This means we have an array of intervention studies available to participants with a variety of clinical diagnoses, such as Mild cognitive impairment (MCI) as well as early and moderate stage Alzheimer's disease.


Our Cores

We are organized into distinct cores that focus on carrying out our multidisciplinary goals and objectives in accordance with our mission.