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Events & Updates

New Microscopy Core Resources

Multiphoton Microscopy

Our new Evident FV5000 Multiphoton system is the first FV5000 MP system in the world, and we are please to be able to offer it to our user base. Advances in live and deep tissue imaging continue to push the limits of conventional microscopy workflows. For researchers working with intact tissue, organoids, or in vivo models, balancing imaging depth, phototoxicity, and acquisition speed remains a persistent challenge.

Our newly available Evident FV5000 upright multiphoton microscope is designed to support demanding imaging applications with:

• Deep tissue multiphoton imaging for intact biological samples
• Simultaneous multicolor acquisition for dynamic experiments
• Reduced photobleaching and phototoxicity during long-term imaging with fast imaging speeds
• SHG/THG label-free imaging capabilities
• Flexible excitation options for diverse fluorophore panels

Applications include:

  • In vivo neuroscience imaging
  • Calcium imaging and neural dynamics
  • Tumor microenvironment studies
  • Organoid and developmental biology workflows
  • Thick tissue and cleared sample imaging

Researchers are using multiphoton workflows to capture biological processes that are difficult to resolve with traditional confocal approaches, including long-duration imaging in living tissue and high-resolution imaging at greater depths. The system is also equipped with single photon confocal abilities and great for standard sample preparations.

We would be happy to schedule:

• A live demonstration
• Sample evaluation imaging
• An application-focused discussion for your workflow
• A technical consultation with an imaging specialist

If you are exploring new approaches for deep tissue or live-cell imaging, we welcome the opportunity to discuss how the FV5000 platform may support your research goals.

 

Slide Scanning Microscopy - Brightfield 
Our new Evident VS200 slide scanner is brightfield only with 210 slide capability. We will now have two VS200 slide scanning systems available to our users. Our original system is brightfield and fluorescence equipped for all applications. It also has a polarizer for polarization microscopy. Please feel free to reach out to us for more details.

 

 

Upcoming Seminars and Workshops

We have several exciting seminars and hands-on workshops coming up this fall. These events are a great opportunity to learn about the latest microscopy and image analysis technologies, see live demonstrations, and explore how these tools can support your research.

Evident FV5000 Informational Lunch and Learn

August 12 | Noon
CNCB Large Conference Room

Join us to learn about the newest addition to our imaging resources: the FLUOVIEW™ FV5000MPE Multiphoton & Confocal Laser Scanning Microscope and how it can advance your research.

Highlights include:

  • Combined multiphoton and confocal imaging
  • 2K resonant scanner and 8K galvo scanner
  • Four SilVIR™ detectors for two-photon imaging
  • Two SilVIR™ detectors for confocal imaging
  • Dual multiphoton lasers:
    • Tunable: 690–1300 nm
    • Fixed: 1045 nm
  • Four confocal lasers: 405, 488, 561, and 640 nm

Please RSVP if you plan to attend and would like lunch.

Imaris Lunch and Learn & Onsite Workshop

Lunch and Learn: August 24 | Noon
CNCB Large Conference Room

Hands-on Workshop: August 24 | 1:30–4:30 PM
CMME Basement Microscopy Core

Discover the newest features in Imaris Version 11 and learn how the software can enhance your image analysis workflows.

To RSVP for lunch and to reserve a workshop spot, contact Tomas Silva at tomas.silva@oxinst.com.

Leica Viventis Deep Light Sheet Seminar

Lunch and Learn: September 2 | Noon
CNCB Large Conference Room

Onsite Workshop: October 8–16
CMME Microscopy Core

Learn about the Leica Viventis Deep Light Sheet system for deep tissue imaging. An onsite workshop will provide an opportunity to test your own samples.

The Viventis Deep platform supports both live and fixed/cleared specimen imaging in a single system by exchanging detection optics. The cleared-sample module accommodates a wide range of clearing media and refractive indices and supports samples up to 9 × 6 × 6 mm. Advanced tiling, stitching, and computational clearing enable high-quality imaging of large specimens while maintaining excellent image quality.

Zeiss LSM 990 Confocal with Lightfield Seminar

Lunch and Learn: October 9 | Noon
CNCB Large Conference Room

Onsite Workshop: October 26 – November 6
CMME Microscopy Core

Learn about the Zeiss LSM 990 with Lightfield 4D, an exciting new technology that captures entire 3D volumes with a single snapshot. The system will be available onsite for live demonstrations.

Lightfield 4D enables instant volumetric imaging at high speed, capturing up to 80 volumes per second while preserving complete spatial and temporal information. This technology is ideal for studying rapid biological processes such as beating hearts, blood flow, neuronal activity, and organism development in unprecedented detail.

Contact Brandon Chechile to schedule a workshop timeslot at brandon.chechile@zeiss.com

 

Past Seminar Links: 

 

 

Citation Guidelines for Using the SOM Microscopy Core

All publications using SOM Microscopy Core resources must cite the following grant numbers:

NS047101, OD030505, OD036455


Example acknowledgment:
Microscopy imaging was performed at the UCSD SOM Microscopy Core
(NS047101, OD030505, OD036455).