Events & Updates
New Microscopy Core Resources
Multiphoton Microscopy
Our newly available Evident FV5000 upright multiphoton microscope is designed to support demanding imaging applications with:
• Deep tissue multiphoton imaging for intact biological samples
• Simultaneous multicolor acquisition for dynamic experiments
• Reduced photobleaching and phototoxicity during long-term imaging with fast imaging speeds
• SHG/THG label-free imaging capabilities
• Flexible excitation options for diverse fluorophore panels
Applications include:
- In vivo neuroscience imaging
- Calcium imaging and neural dynamics
- Tumor microenvironment studies
- Organoid and developmental biology workflows
- Thick tissue and cleared sample imaging
Researchers are using multiphoton workflows to capture biological processes that are difficult to resolve with traditional confocal approaches, including long-duration imaging in living tissue and high-resolution imaging at greater depths. The system is also equipped with single photon confocal abilities and great for standard sample preparations.
We would be happy to schedule:
• A live demonstration
• Sample evaluation imaging
• An application-focused discussion for your workflow
• A technical consultation with an imaging specialist
If you are exploring new approaches for deep tissue or live-cell imaging, we welcome the opportunity to discuss how the FV5000 platform may support your research goals.
We have several exciting seminars and hands-on workshops coming up this fall. These events are a great opportunity to learn about the latest microscopy and image analysis technologies, see live demonstrations, and explore how these tools can support your research.
Lunch and Learn: August 24 | Noon
CNCB Large Conference Room
Hands-on Workshop: August 24 | 1:30–4:30 PM
CMME Basement Microscopy Core
Discover the newest features in Imaris Version 11 and learn how the software can enhance your image analysis workflows.
To RSVP for lunch and to reserve a workshop spot, contact Tomas Silva at tomas.silva@oxinst.com.
Lunch and Learn: September 2 | Noon
CNCB Large Conference Room
Onsite Workshop: October 8–16
CMME Microscopy Core
Learn about the Leica Viventis Deep Light Sheet system for deep tissue imaging. An onsite workshop will provide an opportunity to test your own samples.
The Viventis Deep platform supports both live and fixed/cleared specimen imaging in a single system by exchanging detection optics. The cleared-sample module accommodates a wide range of clearing media and refractive indices and supports samples up to 9 × 6 × 6 mm. Advanced tiling, stitching, and computational clearing enable high-quality imaging of large specimens while maintaining excellent image quality.
Virtual Seminar Sept. 9th at Noon
Register for Virtual Seminar Here
Lunch and Learn Oct. 9th at Noon - CNCB Large Lunch and Learn
Register for Lunch and Learn Here
Onsite Workshop: October 26 – November 6
CMME Microscopy Core
Register to be contacted for a Demo Slot Here
Learn about the Zeiss LSM 990 with Lightfield 4D, an exciting new technology that captures entire 3D volumes with a single snapshot. The system will be available onsite for live demonstrations.
Lightfield 4D enables instant volumetric imaging at high speed, capturing up to 80 volumes per second while preserving complete spatial and temporal information. This technology is ideal for studying rapid biological processes such as beating hearts, blood flow, neuronal activity, and organism development in unprecedented detail.
Past Seminar Links:
- Imaris Seminar: Unlocking the potential of microscopy images with IMARIS AI-powered analysis
- Zeiss 990 Airyscan Confocal and Lightfield Seminar
- Introduction to the new Evident FV5000 Multiphoton System
Citation Guidelines for Using the SOM Microscopy Core
All publications using SOM Microscopy Core resources must cite the following grant numbers:
NS047101, OD030505, OD036455
Example acknowledgment:
Microscopy imaging was performed at the UCSD SOM Microscopy Core
(NS047101, OD030505, OD036455).